实用医学杂志 ›› 2021, Vol. 37 ›› Issue (12): 1587-1591.doi: 10.3969/j.issn.1006⁃5725.2021.12.015

• 临床研究 • 上一篇    下一篇

基于C-TIRADS淋巴结转移的影响因素分析甲状腺乳头状癌出现颈部

刘承开1, 张蕾1, 王晓东2    

  1. 1 广州中医药大学(广州510405);2 广州中医药大学第一附属医院(广州510405)

  • 出版日期:2021-06-25 发布日期:2021-06-25
  • 通讯作者: 王晓东 E⁃mail:9160240@qq.com
  • 基金资助:

    广东省医学科学技术研究基金(编号:B2019050


Risk factors of cervical lymph nodule metastasis on papillary thyroid carcinoma based on C⁃TIRADS 

LIU Chengkai,ZHANG Lei,WANG Xiaodong.    

  1. Department of Ultrasound,the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China 

  • Online:2021-06-25 Published:2021-06-25
  • Contact: WANG Xiaodong E⁃mail:9160240@qq.com

摘要:

目的 2020 8 月我国学者发布了符合中国国情的甲状腺影像报告和数据系统(Chinese Thyroid Imaging Reporting and Data System,C⁃TIRADS),由于该系统发布时间不久,它的应用尚未普及。现本研究利用 C⁃TIRADS 分析甲状腺乳头状癌(papillary thyroid carcinoma,PTC)出现颈部淋巴结转移(cervical lymph nodule metastasis,CLNM)的风险因素,为临床诊断和治疗提供依据。方法 回顾性分析本院194例术后 病理诊断为PTC的结节,根据PTC是否出现颈部淋巴结转移分为转移组和非转移组,对PTC的C⁃TIRADS 分和颈部淋巴结转移之间的关系进行单因素及多因素 logistic 回归分析。结果 转移组患者 C⁃TIRADS 分为 4.0(2.0,5.0),高于非转移组患者(P < 0.01)。经多因素 logistic 回归分析提示,PTC 的患者性别(OR = 0.288,95%CI:0.12 ~ 0.689,P = 0.005)、年龄(OR = 0.964,95%CI:0.936 ~ 0.992,P = 0.011)和 PTC 的大 小(OR = 4.506,95%CI:2.275 ~ 8.922,P < 0.01)、数量(OR = 3.502,95%CI:1.681 ~ 7.296,P = 0.001)及 C⁃TIRADS 评分(OR = 1.948,95%CI:1.227 ~ 3.091,P = 0.005)是 PTC 出现颈部淋巴结转移的独立危险因 素。结论 PTC C⁃TIRADS 评分联合结节数量和大小及患者的性别、年龄对预测其是否出现颈部淋巴结转移具有重要意义。

关键词:

甲状腺乳头状癌, 颈部淋巴结转移, 超声, 中国甲状腺影像报告和数据系统

Abstract:

Objective To study the risk factors of cervical lymph nodule metastasis(CLNM)on papillary thyroid carcinoma(PTC)based on Chinese thyroid imaging report and data system(C⁃TIRADS). Methods A total of 194 patients diagnosed as PTC by surgery and pathological indication were included in the research. All selected participants were divided into lymph nodule metastasis group and lymph nodule negative group respectively accord⁃ ing to the presence of CLNM. Then,the relationship between C⁃TIRADS score of PTC and CLNM was analyzed by univariate and multivariate logistic regression analysis. Results The score of C ⁃TIRADS was 4.0(2.0,and 5.0 among the patients with CLNM,higher than those without cervical lymph nodule metastasis(P < 0.01). Multivariate logistic regression analysis indicated that sex(OR = 0.288,95%CI:0.12~0.689,P = 0.005),age(OR = 0.964 95%CI:0.936~0.992,P = 0.011),size(OR = 4.506,95%CI:2.275~8.922,P < 0.01)and number(OR = 3.502,95% CI:1.681~7.296,P = 0.001)of the nodule and C ⁃ TIRADS score(OR = 1.948,95% CI:1.227 3.091,P = 0.005)were risk factors for CLNM. Conclusion C ⁃ TIRADS score of PTC combined with patients′ sex,age and size and number of the nodule is of great significance in predicting CLNM of PTC. 

Key words:

papillary thyroid carcinoma, cervical lymph nodule metastasis, ultrasound, C?TIRADS ,