实用医学杂志 ›› 2022, Vol. 38 ›› Issue (21): 2681-2685.doi: 10.3969/j.issn.1006⁃5725.2022.21.009

• 临床研究 • 上一篇    下一篇

外周神经脉冲射频与短时程脊髓电刺激治疗带状疱疹后神经痛的疗效

李富波1 张悦1 龚格格2 欧册华1    

  1. 西南医科大学附属医院1 疼痛科,2 物理诊断科(四川泸州646000)

  • 出版日期:2022-11-10 发布日期:2022-11-10
  • 基金资助:
    2022 年四川省自然科学基金项目(编号:2022NSF⁃SC1479)

Comparison of the efficacy of peripheral nerve pulsed radiofrequency and short⁃term spinal cord stimula⁃ tion in the treatment of postherpetic neuralgia

 LI Fubo*,ZHANG Yue,GONG Gege,OU Chehua   

  1. Depart⁃ ment of Painology,Affiliated Hospital of Southwest Medical University,Luzhou 646000,China

  • Online:2022-11-10 Published:2022-11-10

摘要:

目的 比较外周神经脉冲射频与短时程脊髓电刺激治疗带状疱疹后神经痛的疗效及安全性。 方法 纳入2020年1月至2022年1月就诊于西南医科大学附属医院疼痛科的带状疱疹后神经痛患者109 为研究对象,基于倾向性评分匹配分外周神经脉冲射频组(射频组 26 例)与短时程脊髓电刺激组(电刺 激组 26例)。射频组采用超声引导下外周神经脉冲射频,电刺激组在DSA引导下置入电极刺激。比较术后 1周及术后1、3、6个月时的NRS评分与PSQI评分,并观察并发症。结果 与术前比较,两组患者NRS、PSQI 评分在术后各时点降低(均 P < 0.05)。与射频组比较,电刺激组术后 1 个月时 NRS 评分较低(P < 0.05); 术后 1 周、术后 3、6 个月两组 NRS 评分差异无统计学意义。术后各时点 PSQI 评分均较低(均 P < 0.05)。 术后 6 个月时,两组疗效比较,差异无统计学意义(P < 0.05)。结论 外周神经脉冲射频与脊髓电刺激都 能有效缓解带状疱疹后神经痛患者疼痛,中远期疗效无差异,超声引导下外周神经脉冲射频安全性高。

关键词:

带状疱疹后神经痛, 脉冲射频, 脊髓电刺激, 周围神经, 超声

Abstract:

Objective To compare the efficacy and safety of peripheral nerve pulsed radiofrequency and short ⁃term spinal cord stimulation in the treatment of postherpetic neuralgia. Methods The research subjects were 109 patients with postherpetic neuralgia who were treated in the Department of Pain at Southwest Medical University′s Affiliated Hospital from January 2020 to January 2022. Based on propensity score matching,peripheral nerve pulse radiofrequency(26 cases in the radiofrequency group)was compared with that in the radiofrequency group. Short⁃term spinal cord stimulation(26 cases in the electrical stimulation group). The electrical stimulation group received treatment with implanted electrodes under the supervision of DSA,while the radiofrequency group received treatment with peripheral nerve pulsed radiofrequency under the supervision of ultrasonography. The Numerical Rating Scale(NRS)and Pittsburgh Sleep Quality Index(PSQI)scores were compared at 1 week after surgery and at 1,3,and 6 months after surgery,and complications were observed. Results The NRS and PSQI scores of the two groups decreased after operation compared to preoperative(all P < 0.05). The NRS score of the electrical stimulation group was lower at 1 month after surgery compared to the radiofrequency group(P < 0.05); There was no significant difference in the NRS score between the two groups at 1 week,3 and 6 months after surgery. The NRS score of the electrical stimulation group was lower at 1 month after surgery compared to the radiofrequency group(P < 0.05). Conclusion Both peripheral nerve pulsed radiofrequency and spinal cord electrical stimulation can effectively relieve pain in postherpetic neuralgia patients,there was no difference in mid⁃ and long⁃term effica⁃ cy,and the incidence of peripheral nerve pulsed radiofrequency under ultrasound guidance is low.

Key words:

postherpetic neuralgia, pulsed radio frequency, spinal cord stimulation, peripheral nerves, ultrasound