关键词:

甲状腺结节, 中国超声甲状腺影像报告和数据系统, Bethesda 甲状腺细胞病理学报告 系统, 超声造影, BRAFV600E 基因

Abstract:

Objective To explore the diagnostic value of China Ultrasound Thyroid Imaging Reporting and Data System，CEUS and BRAF^V600E gene in Thyroid Cytopathology Reporting System classⅢthyroid nodules. Methods A total of 120 cases of thyroid nodules with preoperative cytopathological diagnosis of TBSRTC classⅢ and postoperative pathology were selected. To compare the diagnostic efficacy of the three methods alone or in com⁃ bination，CEUS，BRAF^V600E gene，and ultrasound C⁃TIRADS grading were performed. Results Single diagnostic method：C⁃TIRADS has higher sensitivity and accuracy than CEUS（P < 0.05）and BRAF^V600E （P > 0.05）；BRAF^V600E has higher specificity than C⁃TIRADS and CEUS（P < 0.05）；Combined diagnosis：The sensitivity，specificity and accuracy of C⁃TIRADS+BRAF^V600E were higher than those of C⁃TIRADS+CEUS and CEUS+BRAF^V600E （P < 0.05）， and the difference was statistically significant. Conclusion Through the use of C ⁃ TIRADS and the BRAF^V600E gene，the diagnostic coincidence rate of benign and malignant TBSRTC class Ⅲ nodules is increased.

Key words:

thyroid nodules, chinese ultrasound thyroid imaging reporting and datasystem, thyroid cy? topathology bethesda reporting system, contrast ultrasound, BRAF^V600E gene