关键词:

腰椎退行性病变, 腰椎融合术, 内固定, 聚醚醚酮棒, 钛棒, Meta 分析

Abstract:

Objective This article systematically evaluates and compares the clinical effects of Polyether⁃ ether ketone（PEEK）rods and titanium rods in lumbar fusion surgery. Methods A computer search of the Chinese Biomedical Literature Database，CNKI，VIP Database，Wanfang Database，PubMed，Embase and Cochrane Library for clinical trials on the use of PEEK rod in lumbar spine fusion for lumbar degenerative lesions，dated all databases will be built until November 2020. Data extraction and quality evaluation of all the included literatures were carried out，and the NOS scale was used to evaluate the methodological quality of 10 studies. Using RevMan5.3 software to conduct meta⁃analysis on JOA score，ODI score，VAS score，fusion rate，intervertebral space height， and operation time. Results A total of 10 studies were included，of which 8 were high quality and 2 were medium quality. Meta⁃analysis showed that there was no significant difference between the two groups in the JOA improve⁃ ment rate in the middle postoperative period（P＞0.05）. In the VAS score of low back pain，the VAS score of low back pain in the titanium rod group was significantly lower at 1 month after surgery（P＜0.05），and there was no significant difference at 6 months（P＞0.05）and 12 months after surgery（P＞0.05）. In the lower limb pain VAS score，there was no significant difference in 1 month（P＞0.05），6 months（P＞0.05）and 12 months（P＞0.05）. The fusion rate in the PEEK rod group was significantly higher than that of the titanium rod group（P＜0.05）. There was no significant difference in the height of the posterior intervertebral space between the two groups at 6 months after surgery（P＞0.05）. Conclusion In lumbar fusion surgery，the use of PEEK rod system could promote verte⁃ bral body fusion，obtain similar therapeutic effects as titanium rod system，and has better lumbar function perfor⁃ mance in the middle postoperative period.

Key words:

lumbar degeneration, lumbar fusion, internal fixation, polyether ether ketone rod （PEEK）, titanium bar, meta analysis