实用医学杂志 ›› 2022, Vol. 38 ›› Issue (5): 560-564.doi: 10.3969/j.issn.1006⁃5725.2022.05.008

• 专题报道 • 上一篇    下一篇

超声、钼靶及两者联合对高级别与中低级别乳腺导管原位癌的诊断价值

武壮壮1,2 张晓娟3 史泽洪1,2 史瑶4 原韶玲2   

  1. 1 山西医科大学(太原 030001);山西医科大学附属山西省肿瘤医院 2 超声科,3 放射科(太原 030013); 4 山西白求恩医院(太原 030032)

  • 出版日期:2022-03-10 发布日期:2022-03-10
  • 通讯作者: 原韶玲 E⁃mail:yuanshaoling08@sina.com

The diagnostic value of ultrasonography,mammography and their combination in high⁃grade and middle⁃ low⁃grade ductal carcinoma in situ

WU Zhuangzhuang*,ZHANG Xiaojuan,SHI Zehong,SHI Yao,YUAN Shaol⁃ing.   

  1. ShanXi Medical University,Taiyuan 030001,China;*Department of Ultrasound,Affiliated Tumor Hospital of Shanxi Medical University,Taiyuan 030013,China

  • Online:2022-03-10 Published:2022-03-10
  • Contact: YUAN Shaoling E⁃mail:yuanshaoling08@sina.com

摘要:

目的 探讨超声、钼靶及两者联合对高级别与中低级别乳腺导管原位癌(ductal carcinoma in situ,DCIS)的诊断价值。方法 选取 2015 1 月至 2020 12 月于我院行乳腺手术、经病理确诊为 DCIS 且术前超声及钼靶影像资料完整的患者161例,共计196个病灶。以术后病理结果为金标准,将其分为高级 DCIS 80 例和中低级别 DCIS 116 例。对两组的超声及钼靶表现进行对比分析。采用受试者工作特 征(ROC)曲线下面积(AUC)分析超声与钼靶单独及联合诊断DCIS的价值结果 超声表现为微钙化在高 级别 DCIS 组占比大,两组差异有统计学意义(P < 0.01);肿块在中低级别 DCIS 组占比大,两组差异有统计 学意义(P < 0.01)。钼靶表现为微钙化在高级别DCIS组占比大,两组差异有统计学意义(P = 0.026)。超声与钼靶单独及联合诊断DCIS的AUC分别为0.783、0.895、0.957。结论 超声及钼靶表现为微钙化与高级别 DCIS相关,超声表现为肿块与中低级别DCIS相关;超声与钼靶联合有助于诊断高级别与中低级别DCIS。

关键词:

乳腺导管原位癌, 高级别, 中低级别, 超声, 钼靶

Abstract:

Objective To investigate the diagnostic value of ultrasonography,mammography and their combination in high⁃grade and middle⁃low⁃grade ductal carcinoma in situ(DCIS). Methods A total of 161 patients with 196 lesions who underwent ultrasound and mammography examination and confirmed by surgical pathology in our hospital between January 2015 and December 2020 were included. Taking pathological diagnosis as the gold standard,196 lesions were divided into high ⁃grade DCIS group(n = 80)and middle ⁃low ⁃grade DCIS group (n = 116). The sonographic and mammographic features were analyzed and compared between the two groups. The area under curve(AUC)of the receiver operating characteristic(ROC)was used to analyze the diagnostic values of ultrasound and/or mammography for the DCIS. Results The percentage of microcalcification of sonography in the high⁃grade DCIS group was significantly higher than that in the middle⁃low⁃grade DCIS group(P < 0.01). The pro⁃ portion of mass of sonography in the high ⁃grade DCIS group was significantly lower than that in the middle ⁃low ⁃ grade DCIS group(P < 0.01). The proportion of microcalcification of mammography in the high⁃grade DCIS group was significantly higher than that in the middle⁃low⁃grade DCIS group(P = 0.026). The AUC of ultrasound and/or mammography for DCIS diagnosis were 0.783,0.895,and 0.957,respectively. Conclusion The ultrasonographic and mammographic features of microcalcification are correlated with high⁃grade DCIS and ultrasonographic features of mass are correlated with middle⁃low⁃grade DCIS. The combination of ultrasound and mammography can help to diag⁃ nostic both high⁃grade and middle⁃low⁃grade DCIS.

Key words:

ductal carcinoma in situ, high grade, middle?low grade, ultrasonography, mammography