Abstract:

Objective To analyze the curative effect and short ⁃ term effect of percutaneous mechanical thrombectomy（PMT）in patients with acute lower extremity arterial ischemia. Methods A retrospective analysis was performed on 74 patients with lower extremity arterial ischemia who were admitted to our department from Janu⁃ ary 2019 to July 2021. Among them，40 were treated with Anjiojet mechanical thrombus aspiration system（PMT group），and 34 with catheter ⁃ directed thrombolysis（CDT group）. The dosage of urokinase，thrombolysis time， hospitalization time，hospitalization cost，postoperative complications，and the incidence of patency and mortality within one month after surgery were compared between the two groups，and 36⁃item short⁃form health survey（SF⁃36） was used to compare the quality of life between CDT group and PMT group. Results The effective rate of surgical treatment in both groups was 100% . The dosage of urokinase in the CDT group and PMT group was（137.41 ± 47.02）× 104 U and（58.35 ± 39.83）× 104 U；thrombolysis time was（35.85 ± 11.60）h and（22.30 ± 11.82）h； hospitalization time was（10.31 ± 2.9）days and（8.55 ± 2.11）days；hospitalization expenses were（3.32 ± 1.12） ten thousand yuan and（5.22 ± 0.89）ten thousand yuan and the incidence of bleeding and puncture bleeding were 17.6% and 2.5%，respectively. SF⁃36 showed that the score of body pain was（53.86 ± 13.89）and（63.02 ± 10.39）， and that of emotional function（58.04 ± 10.32）and（63.61 ± 13.19）respectively in the two consecutive days after the operation，and the differences were statistically significant（P < 0.05）. There was no significant difference in patency rate（88.2% vs. 90.0%）and fatality rate（3.0% vs. 5.0%）within one month（P > 0.05）. Conclusion In the treatment of acute lower extremity arterial ischemia，AngioJet can significantly reduce postoperative bleeding and puncture point hematoma，shorten hospitalization time，and reduce operation cost while ensuring the same efficacy as CDT，and improve the quality of life of patients after operation.

Key words:

acute lower limb ischemia, AngioJet, clinical efficacy