Abstract:

Objective To analyze the effects of Shoutai Pill on endometrial receptivity and the related factors in infertile patients with polycystic ovary syndrome（PCOS）induced by kidney deficiency. Methods A total of 116 infertile patients with PCOS induced by kidney deficiency in our hospital from February 2020 to February 2022 were prospectively included in the study. According to the envelope extraction method，they were divided into control group（54 cases）and Shoutai Pill group（62 cases）. Patients in the control group were orally treated with letrozole，and those in the Shoutai Pill group with Shoutai Pill and letrozole. After bejing treated for three menstrual periods，ovulation rate，pregnancy rate，follicular development，endometrial receptivity，the level of related factors and the efficacy of the two groups were compared. Results （1）After treatment，the total number of cycles，the ovulation rate and pregnancy rate of the Shoutai Pill group were higher than those of the control group（P < 0.05）. （2）The follicle diameter，the number of mature follicles and the number of dominant follicles in the Shoutai Pill group were higher than those in the control group（P < 0.05）.（3）The endometrial thickness（Em）of the Shoutai Pill group was greater than that of the control group（P < 0.05）；the uterine artery pulsatility index（PI）and uterine artery resista ⁃ nce index（RI）were lower than those of the control group（P < 0.05）.（4）Serum SHBG level of the Shoutai Pill group was higher than that in the control group（P < 0.05），while the serum levels of T，LH，FSH and the visfatin were lower than those of the control group（P < 0.05）.（4）The total effective rate of the Shoutai Pill group was higher than that of the control group（P < 0.05）. Conclusion Shoutai Pill can effectively improve endometrial receptivity，the level of related factors and follicular development，and increase vulation rate and pregnancy rate.

Key words:

Shoutai Pill, kidney deficiency, polycystic ovary syndrome, infertility, endometrial receptivity