The Journal of Practical Medicine ›› 2021, Vol. 37 ›› Issue (22): 2893-2897.doi: 10.3969/j.issn.1006⁃5725.2021.22.013

• Clinical Research • Previous Articles     Next Articles

Analysis of risk factors for No.253 lymph node metastasis in colorectal cancer patients

ZHANG Jianfeng*， GAO Xiangxin，WU Xueliang，MA Hongqing，HU Xuhua，MENG Zesong，ZHANG Pengfei，TANG Yujie，WANG Guiying.   

  1. The Second Department of General Surgery，the Fourth Hospital of Hebei Medical University，Shijiazhuang 050011，China

  • Online:2021-11-25 Published:2021-11-25
  • Contact: WANG Guiying E⁃mail：13932186739@139.com​
  • Supported by:


Abstract:

Objective To explore the risk factors related to No.253 lymph node metastasis，in order to provide reference for No.253 lymph node dissection. Methods The data of 205 patients with colorectal cancer who underwent radical resection in our department from September 2017 to April 2019 was retrospectively analyzed. The clinicopathological factors that may affect lymph node metastasis of No.253 were selected for risk factor analysis. Results Univariate analysis data showed that No.253 lymph node metastasis was significantly related to the distance from the tumor to the anal margin，preoperative serum CEA，preoperative serum CA19⁃9，T stage，vascular tumor thrombus and nerve invasion（P＜0.05）. Multivariate Logistic regression analysis results demonstrated that vascular tumor thrombus［OR＝8.506，95%CI（1.841，39.302）］was an independent risk factor for No.253 lymph node metastasis. Conclusion Vascular tumor thrombus is an independent risk factor for No.253 lymph node metas⁃ tasis. It could be an important reference factor for selective No.253 lymph node dissection.

Key words: colorectal cancer,  , No.253 lymph node,  , risk factors