Abstract:

Objective To study clinical curative effect of YiqiYangying Decoction used in perioperation for cases of severe knee osteoarthritis treated by artificial knee resurfacing surgery. Methods According to the in⁃ clusion and exclusion criteria，82 patients with severe knee osteoarthritis were randomly assigned to one of two groups：the control group and the YiqiYangying Decoction observation group. Patients in the control group under⁃ went artificial knee resurfacing surgery with conventional enhanced recovery after surgery. In the observation group，patients were given YiqiYangying Decoction for seven days in addition to the above ⁃mentioned treatment. To take statistical analysis of RBC，HGB，D⁃dimer of the patients in the two groups before，one day and eight days after the surgery. To compare knee range of motion，VAS and Lequesne MG of the patients in the two groups before and eight days after the surgery. Results RBC and HGB levels in both groups were significantly lower one day after surgery than before. RBC and HGB levels in both groups were significantly lower one day after surgery than before. RBC and HGB levels in the two groups were significantly higher eight days after surgery than one day after surgery. The RBC and HGB of the observation group were significantly higher than those of the control group. D⁃ dimer of the two groups one day after the surgery was significantly higher than before surgery and D⁃ dimer of the two groups eight days after the surgery was significantly lower than one day after the surgery. D⁃dimer of the the observation group was significantly lower than the control group. Knee range of motion of the two groups eight days after the surgery was significantly higher than before operation. Knee range of motion of the observation group was significantly higher than the control group. VAS and Lequesne MG of the two groups eight days after the surgery was significantly lower than before operation. VAS and Lequesne MG of the observation group was significantly lower than the control group. Twenty⁃six inpatients were cured and there were 12 inpatients of conspicuity in the observa⁃ tion group while 20 of cure and 13 of conspicuity in the control group. The rate of cure and conspicuity of the obser⁃vation group was significantly higher than the control group. Conclusion On the one hand，anemia and blood coagulation function were significantly improved，as was the curative effect of TCM diseases and syndromes；on the other hand，pain was relieved and joint motor function was significantly improved. YiqiYangying Decoction could be used to improve recovery after surgery in cases of severe knee osteoarthritis treated effectively with artificial knee resurfacing surgery.

Key words: knee osteoarthritis（KOA）,  , YiqiYangying Decoction,  , artificial knee resurfacing surgery （AKRS）,  , enhanced recovery after surgery（ERAS）,  , venous thromboembolism（VTE）