实用医学杂志 ›› 2021, Vol. 37 ›› Issue (13): 1742-1745.doi: 10.3969/j.issn.1006⁃5725.2021.13.020

• 医学检查与临床诊断 • 上一篇    下一篇

实时剪切波弹性成像和超声造影技术单独及联合诊断在乳腺癌中的应用价值

巩海燕1, 周文斌2 ,邓晶1, 栗翠英1, 杜丽雯1, 王慧1   

  1. 南京医科大学第一附属医院1 超声科,2 乳腺外科(南京 210029)

  • 出版日期:2021-07-10 发布日期:2021-07-10
  • 通讯作者: 王慧 E⁃mail:lovelywanghui@163.com
  • 基金资助:

    国家自然科学基金(编号:8177070772


Diagnostic values of shear wave elastography and contrast⁃enhanced ultrasound techniques for breast can⁃ cer

GONG Haiyan,ZHOU Wenbin,DENG Jing,LI Cuiying,DU Liwen,WANG Hui.    

  1. Department of Ultraso⁃ nography,Nanjing Medical University First Hospital,Nanjing 210029,China 

  • Online:2021-07-10 Published:2021-07-10
  • Contact: WANG Hui E⁃mail:lovelywanghui@163.com
  • Supported by:


摘要:

目的 探讨实时剪切波弹性成像(SWE)和超声造影(CEUS)技术单独及联合诊断乳腺癌的 应用价值。方法 选取 2015 4 月至 2018 12 月我院收治的 112 例乳腺肿瘤患者(共 112 个乳腺肿块), 按病理学检查结果分为良性肿块组 65 例,恶性肿块组 47 例。两组患者均行 SWE 以及 CEUS 检查。采用 受试者工作特征(ROC)曲线下面积(AUC)分析 SWE CEUS 图像单独及联合诊断乳腺癌的诊断价值。 结果 恶性肿块组平均弹性值、最大弹性值、峰值强度及明显减退时间明显高于良性肿块组(P < 0.05), 达峰时间明显低于良性肿块组(P < 0.05);两组患者最小弹性值比较差异无统计学意义(P > 0.05)。SWE CEUS 图像单独及联合诊断乳腺癌的 AUC 值分别为 0.766、0.818、0.896。结论 SWE CEUS 技术对乳腺癌具有一定诊断价值,且两者联合应用有利于提高诊断准确率。

关键词:

 , SWE, CEUS, 联合诊断, 乳腺癌, 应用价值

Abstract:

Objective To explore the values of real⁃time shear wave elastography(SWE)and/or contrast⁃ enhanced ultrasound(CEUS)techniques in the diagnosis of breast cancer. Methods One hundred and twelve breast tumor patients with a total of 112 breast masses hospitalized in our hospital from April 2015 to December 2018 were divided into benign mass group(n = 65)and malignant mass group(n = 47)according to the pathological examination results. SWE and CEUS were performed in both groups. The area under curve(AUC)of the receiver operating characteristic(ROC)was used to analyze the diagnostic values of SWE and/or CEUS for the breast masses. Results The average elasticity,maximum elasticity,peak intensity,and time of significant decline in the malig⁃ nant mass group were significantly higher than those in the benign mass group(P < 0.05),and the peak time was significantly lower than that of the benign mass group(P < 0.05). There was no statistically significant difference in the minimum elasticity value between the two groups(P > 0.05). The AUC of SWE and CEUS for breast cancer diagnosis were 0.766,0.818,0.896,respectively. Conclusion Both SWE and CEUS have certain diagnostic value when used alone in the diagnosis of breast cancer,and their combined application is conducive to improving the accuracy of diagnosis.

Key words: SWE,  , CEUS,  , combined diagnosis,  , breast cancer, application value