关键词: 股骨头坏死, 早期, β?磷酸钙, 富血小板血浆

Abstract:

Objective The research tried to investigate the reliability of platelet⁃rich plasma compositesβ⁃alcium phosphate for the treatment of early Osteonecrosis of the Femoral Head. Methods 108 patients of earlyOsteonecrosis of the Femoral Head（unilateral lesion）were randomly divided into compound group（52 cases）andcontrol group（56 cases）. The control group was treated with osteonecrosis bone scraping，biomaterials β⁃alciumphosphate particles filling and pressing as well as β⁃alcium phosphate columnar ceramic rod implantation. Thecomposite group mixed biomaterials β ⁃alcium phosphate particles to match platelet⁃ich plasma filling andcompression and columnar calcium phosphate ceramic rod implantation. The VAS and Harris scores，imaging evalu⁃ation and quantitative indexes were compared between the two groups. Results Compared with multiple time sitesin 24 months after operation，the implant mineralization and new bone crawling growth replacement in the compos⁃ite group were significantly better than those in the control group（P < 0.05）. The VAS and Harris in the compositegroup were also better than those in the control group（F = 30.12，17.88，P＜0.05）. Conclusion Platelet⁃richplasma composites β⁃alcium phosphate have a reliable advantage in the treatment of early Osteonecrosis of theFemoral Head，which could accelerate the growth and mineralization of new bone crawling，promote the fusion ofcalcium phosphate implants with their own host bone and facilitate functional recovery.

Key words: osteonecrosis of the femoral head, early metaphase, biological materials?β?calcium phos?phate, platelet?rich plasma