Abstract:

Objective The purpose of this study was to see how different doses of sufentanil combined with dexmedetomidine affected agitation after adenoidectomy in children. Methods Eighty⁃one children with adenoid hypertrophy were randomly divided into three groups according to different doses of sufentanil. During anesthesia induction，group A was given sufentanil 0.1 μg/kg，group B was given sufentanil 0.2 μg/kg，group C was given suf⁃ entanil 0.3 μg/kg. After induction，the three groups were combined with dexmedetomidine 0.5 μg/kg ，sevoflurane combined with remifentanil was used for anesthesia maintenance. The incidence of agitation and adverse reactions after extubation were recorded. Results Compared with group A，the incidence of agitation，FLACC score of early postoperative analgesia ，the number of additional analgesics and the incidence of cough after extubation were lower in group B and group C（P < 0.05）. Compared with group C，the recovery time of spontaneous breathing，extubation time and PACU stay time of group A and group B were shorter（P < 0.05）. Conclusion In children，sufentanil 0.2 μg/kg combined with dexmedetomidine reduces agitation and improves safety during adenoidectomy.

Key words:

 , children, adenoidectomy, sufentanil