微塑料在肥胖领域的研究进展

doi:10.3969/j.issn.1006-5725.2024.14.002

Abstract

Abstract:

Overweight and obesity have emerged as a significant public health concern globally. While factors such as genetics， diet， and physical activity are insufficient to fully account for the rise in overweight and obesity， recent studies have indicated a link between environmental pollutants and the development of obesity. Microplastics， a novel type of environmental pollutant， are pervasive in various environmental media and daily life， entering organisms through multiple pathways including the digestive tract， respiratory tract， skin， among others. Evidence from studies has revealed the presence of microplastics in human tissues， organs， and biological samples， suggesting potential health risks to humans. This review outlines the pathways and distribution of microplastics within the human body while summarizing current research progress in relation to obesity. This article aims to raise awareness within society regarding the detrimental effects of microplastics and provide a theoretical foundation for medical professionals addressing public health issues.

Key words: microplastics, obesity, public health

CLC Number:

X505

Shulei ZHANG,Ruiji CUI,Lingjun YAN,Wei SUN,Yinglong. BAI. Research progress of microplastics in the field of obesity[J]. The Journal of Practical Medicine, 2024, 40(14): 1908-1915.

Figures/Tables 1

Tab.1

References 69

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名称	聚合物	数量/浓度	形状	尺寸	参考文献
鼻腔灌洗液	室内：PVC、PA 室外：PA、PE	室内：2.6 particles/g 室外：0.8 particles/g	纤维、碎片	未提及	［31］
痰液	室内：PVC、PA 室外：PVC、PA	室内：134.3 particles/g 室外：102.9 particles/g	纤维、碎片	未提及	［31］
唾液	PU、PP、PET	0.3 MPs/individual	纤维	< 100 μm	［32］
肺	PP、PET	（0.7 ± 0.8） MP/g of tissue	纤维、碎片	12 ~ 2 475 μm	［33］
肝脏、肾脏、脾脏	PS、PVC、PET	1.4 particles/g tissue	碎片	4 ~ 30 μm	［34］
结肠切除术样本	PC、PA、PP	（28.1 ± 15.4） particles/g tissue	纤维、丝状	0.8 ~ 1.6 mm	［35］
睾丸	PS	（11.6 ± 15.5） particles/g	碎片	20 ~ 100 μm	［35］
精液	PE、PVC	（0.2 ± 0.5） particles/mL	纤维、碎片、薄膜	20 ~ 100 μm	［35］
母乳	PE、PVC、PP	0 ~ 2.7 MP/g	球形、不规则片段	571 ~ 3 000 μm	［36］
头发	PP、PET	> 3.5 MPs/individual/day	纤维	< 100 μm	［32］
静脉组织	AR、PVA、PU	（29.3 ± 34.9） MP/g tissue	不规则片段	16 ~ 1 074 μm	［37］
血液	PET、PS、PE	1.6 μg/mL	未提及	≥ 700 nm	［38］
血栓	Phthalocyanine、LDPE	1 ~ 15 particles/tissue	不规则块状	2.1 ~ 26.0 μm	［39］
胎盘	PA、PU	18 MPs/g	球形、不规则片段	< 50 μm	［40］
胎粪	PA、PU	51.4 MPs/g	球形、不规则片段	< 50 μm	［40］
	PET	3 200 ~ 12 000 ng/g dw	未提及	未提及	［41］
	PC	110 ng/g dw	未提及	未提及	［41］
婴儿粪便	PET	36 000 ng/g dw	未提及	未提及	［41］
	PC	78 ng/g dw	未提及	未提及	［41］
成人粪便	PP、PET、PS	20 MPs/10 g of stool	碎片、薄膜	50 ~ 500 μm	［42］
	PET	2 600 ng/g dw	未提及	未提及	［41］
	PC	110 ng/g dw	未提及	未提及	［41］

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Research progress of microplastics in the field of obesity

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