关键词: 肝细胞肝癌, 营养, ESPEN标准, 肝硬化, 预后

Abstract: Objective To evaluate the nutritional risk assessment form（NRS⁃2002），the malnutrition universal screening form（MUST），the patient subjective overall assessment form（PG⁃SGA），and the controlled nutritional status score（CONUT）to evaluate liver based on ESPEN standards. The preoperative nutritional status of patients with hepatocellular carcinoma and further explore its correlation with prognosis. Methods A total of 245 patients with HCC who were treated in our hospital from January 2014 to January 2017 were selected. All patients were screened for nutrition within 24 hours of admission. Collect NRS⁃2002，MUST，PG⁃SGA，and CONUT scores. Results The Kappa values of NRS⁃2002，MUST，PG⁃SGA，CONUT and ESPEN standards are：0.339，0.426，0.483，0.483. Multivariate Cox proportional hazard regression showed that BMI，liver cirrhosis（yes），tumor
staging（Ⅱ⁃Ⅲ），ESPEN standard（malnutrition），PG⁃SGA（malnutrition），and CONUT（malnutrition）were in⁃dependent risk factors for recurrence in HCC patients（P < 0.05）Cirrhosis（yes），ESPEN standard（malnutrition），PG⁃SGA（malnutrition），and CONUT（malnutrition）were independent risk factors for death in patients with HCC（P < 0.05）. Conclusion Both PG⁃SGA and CONUT can be used as preoperative nutrition screening tools for HCC patients，and they are related to postoperative recurrence and death. However，the clinical application of pg⁃sga is complicated and the consistence of conut is high. It is recommended to use conut as a nutritional screening tool.

Key words: hepatocellular carcinoma, nutrition, ESPEN criteria, Cirrhosis of the liver, prognosis