Abstract:

The incidence of perioperative arrhythmias is 4%~20% in noncardiac surgery and 10% ~ 30% in cardiothoracic surgery， with the incidence of perioperative arrhythmias in cardiac surgery patients as high as 90%. Perioperative arrhythmias can prolong hospitalization and increase morbidity and mortality during hospitalization. Studies have shown that aberrantly expressed microRNAs in cardiovascular diseases can participate in cardiac automaticity， excitability and conductivity by regulating ion channels， gap junction proteins， and intracellular Ca²⁺ handling proteins， thereby regulating cardiac electrophysiological homeostasis and arrhythmias. In this article， we will review the research progress of microRNAs and arrhythmias mainly from the perspective of cardiac electrophysiological imbalance.

Key words: microRNA, cardiac electrophysiology, arrhythmia