Abstract:

Objective To evaluate the 5⁃year efficacy and safety of transurethral plasmakinetic enucleation of the prostate（PKEP）with anterior lobe preservation in the treatment of benign prostatic hyperplasia（BPH）. Methods 100 patients with BPH were divided into two groups：transurethral plasmakinetic resection of prostate （PKRP group，n = 50）and PKEP preserving anterior lobe（PKEP group，n = 50）. The operation time，intraopera⁃ tive blood loss，resected tissue weight，international prostate symptom score （I ⁃ PSS），quality of life score （QOL），residual urine volume（RUV）and maximum urinary flow rate（Qmax）3 months to 5 years after opera⁃ tion were compared between the two groups. Results compared with PKRP group，the operation time of PKEP group was shorter，the amount of intraoperative blood loss was less，and the weight of resected tissue was larger（all P < 0.001）. There was no significant difference in IPSS，RUV and QOL between the two groups at 3 months，half a year and 1 year after operation，but 3 and 5 years after operation，the IPSS，RUV and QOL in the PKEP group were better than those in the PKRP group. The Qmax of PKEP group was better than that of PKRP group in all postoperative periods. There was no significant difference in IPSS，RUV，QOL and Qmax in each period in PKEP group（P > 0.05）. There was no significant difference in PKRP group at 1 year after operation，but there was signifi⁃ cant difference in 3 years and 5 years after operation（P < 0.05）. Conclusion Anterior lobe preserved PKEP is an effective treatment for BPH，with shorter operation time，less intraoperative blood loss and complications，and obvious and stable efficacy in relieving voiding obstruction and lower urinary tract symptoms.

Key words: