低强度脉冲超声调控治疗疼痛性膝骨关节炎的临床研究

doi:10.3969/j.issn.1006-5725.2023.21.015

Abstract

Abstract:

Objective To explore the clinical efficacy and safety of low-intensity pulse ultrasound in the treatment of medial painful knee osteoarthritis. Methods A total of 10 patients with medial painful knee osteoarthritis were collected and treated with low-intensity pulsed ultrasound. VAS visual analogue scores， WOMAC and Lysholm knee osteoarthritis rehabilitation scale scores were performed before treatment， immediately after treatment， 1 week， 2 weeks and 4 weeks after treatment. The efficacy and safety were compared before and after treatment. The ultrasound images before and after treatment were compared to verify its safety. Result VAS， WOMAC and Lysholm scores were statistically significant before and immediately after treatment， 1 week and 2 weeks after treatment （P　<　0.05）， but there was no statistically significant difference between them and 4 weeks after treatment （P > 0.05）. VAS decreased significantly before treatment， immediately after treatment， 1 week after treatment and 2 weeks after treatment， and were （5.26　±　1.12），（2.76　±　0.92），（2.74　±　1.26），（3.42　±　0.93）， respectively. The secondary outcome indicators of WOMAC and Lysholm were significantly changed before treatment， immediately after treatment， 1 week after treatment and 2 weeks after treatment. They were （24.03　±　4.43） and （66.93　±　14.14），（12.75　±　1.63） and （79.86　±　10.82），（12.76　±　1.82） and （81.93　±　7.67），（15.17　±　2.73） and （77.08　±　9.73）， respectively. No significant abnormality was found in the ultrasound images before and after treatment. Conclusion low-intensity pulsed ultrasound safely and effectively regulates the peripheral knee nerve in the treatment of painful knee osteoarthritis， providing a new idea for the intervention and treatment of clinical knee osteoarthritis.

Key words: low intensity pulsed ultrasound, knee osteoarthritis, genicular nerve

CLC Number:

R454.4

Shanshan HU,Xiao LIU,Hancai LUO,Yayun WU,Xiaoman WU,Lili NIU,Min PAN. Clinical study of low intensity pulsed ultrasound in the treatment of painful knee osteoarthritis[J]. The Journal of Practical Medicine, 2023, 39(21): 2783-2789.

Figures/Tables 5

Tab.1

Fig.1

Fig. 2

Tab.2

Fig.3

References 32

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组别	例数	年龄（岁）	身高（m）	体重（kg）	BMI（kg/m²）	疼痛持续时间（月）
A组	15	65.12 ± 10.34	1.65 ± 0.076	63.04 ± 8.10	23.20 ± 2.15	2.13 ± 0.72
B组	10	62.26 ± 11.92	1.72 ± 0.08	67.03 ± 12.96	23.63 ± 3.26	2.14 ± 0.93

项目	组别	例数	治疗前	治疗后即刻	治疗后1周	治疗后2周	治疗后4周
VAS	A组	15	5.26 ± 1.12	2.76 ± 0.92^*	2.74 ± 1.26^#	3.42 ± 0.93^&	4.05 ± 0.76
	B组	10	5.54 ± 1.28	4.64 ± 1.53	5.23 ± 1.17	4.76 ± 1.34	5.33 ± 1.04
Lysholm	A组	15	66.93 ± 14.14	79.86 ± 10.82^*	81.93 ± 7.67^#	77.08 ± 9.73^&	65.36 ± 22.10
	B组	10	67.83 ± 10.05	66.44 ± 13.67	70.61 ± 15.96	70.92 ± 8.96	68.74 ± 11.31
WOMAC疼痛	A组	15	8.04 ± 1.87	2.73 ± 1.15^*	2.94 ± 0.48^#	3.47 ± 0.74^&	6.67 ± 1.34
	B组	10	7.43 ± 1.96	5.62 ± 1.40	5.72 ± 1.67	6.32 ± 2.17	6.58 ± 1.23
WOMAC僵硬	A组	15	1.93 ± 0.48	1.00 ± 0.32^*	0.60 ± 0.24^#	1.26 ± 0.33	1.68 ± 0.34
	B组	10	1.86 ± 0.57	1.60 ± 0.47	1.85 ± 0.30	2.17 ± 0.53	1.92 ± 0.47
WOMAC日常活动	A组	15	17.24 ± 7.03	9.21 ± 3.92^*	8.91 ± 3.09^#	10.46 ± 2.82^&	15.61 ± 5.86
	B组	10	16.78 ± 6.45	14.62 ± 5.34	15.53 ± 6.08	15.45 ± 5.67	15.62 ± 5.66
WOMAC总分	A组	15	24.03 ± 4.43	12.75 ± 1.63^*	12.76 ± 1.82^#	15.17 ± 2.73^&	22.41 ± 4.47
	B组	10	23.72 ± 3.69	20.48 ± 2.62	20.91 ± 2.95	21.35 ± 3.06	21.62 ± 2.96

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Clinical study of low intensity pulsed ultrasound in the treatment of painful knee osteoarthritis

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