Abstract:

Objective To explore the efficacy of elastic intramedullary nail and lesion curettage combined with autologous bone marrow and allogeneic bone powder transplantation in the treatment of proximal humeral bone cysts in children. Methods A retrospective analysis was performed on the clinical data of 56 children（observation group）with proximal humeral bone cysts who received elastic intramedullary nail and lesion curettage combined with autologous bone marrow and allogeneic bone powder transplantation in our hospital between July 2018 and September 2020，and the clinical data of 51 children who underwent single lesion curettage combined with autolo⁃ gous bone marrow and allogeneic bone powder transplantation in our hospital during the same period were included in control group（n = 51）. The differences in postoperative efficacy and healing time were compared between the two groups；the complications were explored in the two groups，and the differences in limb function［Musculoskeletal Tumor Society（MSTS）function score］and quality of life［Pediatric Quality of Life Inventory TM version 4.0（Ped⁃ sQLTM 4.0）］of the two groups were analyzed before surgery and 6 months after surgery. Results Six months after surgery，the cure rate of children in the observation group was higher than that of the control group，and the cure time of children in observation group was shorter than that of control group（all P < 0.05）. There were no significant differences in the incidence rates of treatment complications between the two groups during 6 months of follow⁃up（all P > 0.05）. Six months after surgery，the scores of MSTS and PedsQLTM 4.0 of the two groups were increased when compared with those before surgery，and the scores in observation group were higher than those in control group（all P < 0.05）. Conclusion Elastic intramedullary nail and lesion curettage combined with autolo⁃ gous bone marrow and allogeneic bone powder transplantation has a significant efficacy in the treatment of proximal humeral bone cysts in children，and it shortens the healing time and improves the limb function and the quality of life，and will not lead to increased complications.

Key words:

elastic intramedullary nail, lesion curettage, autologous bone marrow, children, bone cysts, proximal humerus