The Journal of Practical Medicine ›› 2021, Vol. 37 ›› Issue (7): 899-902.doi: 10.3969/j.issn.1006⁃5725.2021.07.014

• Clinical Research • Previous Articles     Next Articles

Predictive value of serum calcium combined with procalcitonin clearance in the short⁃term prognosis of pa⁃ tients with septic shock in ICU

SUN Caizhi,WEI Jingjing,ZHU Jin,ZHANG Zheng   

  1. Department of Emergen⁃ cy,Nanjing Hospital Affiliated to Nanjing Medical University,Nanjing 210006,China

  • Online:2021-04-10 Published:2021-04-10
  • Contact: ZHANG Zheng E⁃mail:zz18351891108@126.com

Abstract:

Objective To investigate the predictive value of serum calcium combined with PCTc in the short⁃term prognosis of septic shock patients. Methods The patients of septic shock admitted to ICU were enrolled. The APACHE Ⅱ scores within 24 hours was collected after admission,the serum calcium and PCT0 h were collected at the time of admission. In addition,procalcitonin was collected 24 h after treatment(PCT24 h)and the 24 h PCTc was calculated. The patients were divided into survival group and death group according to the prognosis during ICU hospitalization. ROC curve was drawn to analyze the diagnostic efficacy of the above indicators for the short ⁃ term prognosis of septic shock patients. Results Compared to the survival group,PCT24 h was significantly higher in the death group(P < 0.05),the serum calcium and PCTc were lower in the death group(P < 0.05). The level of serum calcium,PCTc and serum calcium combined with PCTc were significantly negatively correlated with the APACHEⅡ score,with the strongest correlation of serum calcium combined with PCTc(P < 0.05). ROC curve analysis showed that the diagnostic value of serum calcium combined with PCTc was the largest. Conclusion Serum calcium and PCTc are effective prognostic indicator of ICU mortality during hospitalization for septic shock patients,and the combination of them has the higher evaluation value.

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