Abstract:

Objective The aim of this study was to investigate the clinical value of non⁃invasive hemody⁃namics monitoring system（NICaS）in hemodynamics of patients with moderate to severe acute paraquat pesticide（APP）. Methods A total of 102 patients with moderate to severe APP admitted to the emergency department inour hospital from January 2019 to March 2020 were enrolled and randomly divided into non⁃invasive hemodynamicgroup（NICaS group，36 cases），lung thermal dilution group（Picco group，32 cases）and empirical treatmentgroup（34 cases）. The relationships among hemodynamics，survival rate and complications were analyzed. Results The patients age，sex ratio，body mass index（BMI），heart rate，systolic blood pressure，treatment period andadmitted to hospital with acute physiology and chronic health evaluation Ⅱ（APACHE Ⅱ）score were all no statis⁃tical difference among three groups（P > 0.05）. Compared with the experience group，the in⁃hospital mortality ofAPP patients in NICaS group and Picco group was significantly lower（P < 0.05）. The Cardiac output（CO）wassignificantly correlated with peripheral vascular resistance index （SVRI） at the same time point measured by NICaS and Picco methods. This correlation was more obvious in the interval of 2.7 ~ 6.8 L/min（r = 1.000，P＜0.001）and 520 ~ 2 367 dyn·s·cm⁃5·m2（r = 1.000，P＜0.001）. Bland⁃altmen analysis showed that the consistencyof CO measured by Picco and NICaS was 93.75%（P = 0.278）and that of SVRI was 96.88%（P = 0.579）. Comparedwith the experience group，the average daily infusion volume and daily colloid infusion volume of patients in NICaSgroup and Picco group were lower and the differences were statistically significant（P < 0.05）. Comparison betweenthe groups showed that the first cardiac output was statistically different（P < 0.05）. Conclusion The use of non⁃invasive hemodynamic monitoring system could effectively，quickly and safely monitor hemodynamic indexes in therescue of patients with moderate to severe APP.

Key words: hemodynamics, noninvasive technology, monitoring system, acute paraquat pesticidepoisoning（APP）, clinical guidance, prognosis