Abstract:

Objective Evaluation of the short term efficacy of fully degraded sinus drug ⁃stents（SES） implanted during modified endoscopic sinus surgery （ESS）in patients with Recurrent Rhinosinusitis （RRS）. Methods Patients with recurrent sinusitis who were operated by the same surgeon were selected and randomly divided into stent side and control side after ESS by self⁃control method. At 30 and 90 days after surgery ，an independent evaluation team evaluated the recovery of the stent and control sites based on the endoscopic findings， performed endoscopic scores（VAS），and determined the need for postoperative intervention（surgery and oral hormone intervention）. Results A total of 30 patients with recurrent sinusitis were included in this study. At 30 days after surgery，the proportion of patients requiring postoperative intervention in the stent group decreased by 50% compared with the control group（χ2 = 5.514，P = 0.007 0），including 50% for surgical intervention（χ2 = 4.921， P = 0.043 9）and 50% for oral hormone intervention（χ2 = 5.292，P = 0.022 7）. The patency of frontal sinus was increased by 60%（χ2 = 5.343，P = 0.034）. At 90 days post⁃ESS，the proportion of postoperative intervention in the stent group decreased by 50% compared with the control group（χ2 = 5.414，P = 0.024 5），among which，surgical intervention decreased by 42.8%（χ2 = 4.887，P = 0.033 9），and oral hormone intervention decreased by66.7% （χ2 = 5.492，P = 0.042 7）. The patency of frontal sinus opening was increased by 44.4%（χ2 = 4.343，P = 0.044）， and the inflammation score（VAS）was significantly different（χ2 = 5.242，P = 0.035）. Conclusion The implan⁃ tation of SES in RRS improves the postoperative patency of frontal sinus，reduces the possibility of reintervention after ESS and postoperative inflammatory response，and the short⁃term effect of SES in the treatment of recurrent sinusitis is effective.

Key words:

recurrent rhinosinusitis, full endoscopic sinus surgery, bioabsorbable steroid ?eluting sinus stent