The Journal of Practical Medicine ›› 2022, Vol. 38 ›› Issue (17): 2170-2180.doi: 10.3969/j.issn.1006⁃5725.2022.17.010

• Clinical Research • Previous Articles     Next Articles

Mutually actingrisk roles of oral cleanliness and stroke ⁃associated pneumonia in patients with acute isch⁃ emic stroke:A case ⁃control study

YANG Xiaohua*,CHEN Huijuan,HE Juan,ZHANG Juan,HU Tingting, YANG Xiaoli,WANG Qing,TAO Xi.    

  1. Department of Neurology,Zhujiang Hospital,Southern Medical University Guangzhou 510282,China

  • Online:2022-09-10 Published:2022-09-10
  • Contact: TAO Xi E⁃mail:taoxi567@hunnu.edu.cn

Abstract:

Objective To analyze the influencing factors and correlation of oral hygiene and stroke⁃associ⁃ ated pneumonia(SAP)in patients with acute ischemic stroke. Methods We performed a cross⁃sectional study by recruiting 331 patients with acute ischemic strokefrom two medical centers. A series of assessments were performed to evaluate the neurological status and habits of oral hygiene. Univariate analyses were performed firstly on the conditions of oral hygiene and occurrence of SAP. Multiple logistic regression analyses were conducted to find risk factors of oral cleanness and SAP in the stroke patients. Results After adjusting the confounders,multivariable logistic regression analysis showed that SAP(OR = 2.219,P = 0.026),dental caries(OR = 1.292,P = 0.005)and age(OR = 1.030,P = 0.006)were the risk factors for oral cleanness in those stroke patients,while the score of Barthel index(OR = 0.986,P = 0.019)was a protective factor. BOAS score(OR = 1.972,P < 0.001)and NIHSS score(OR = 1.322,P < 0.001)were the risk factors for SAP. Conclusion The abnormality of oral cleanness and SAP are the and mutually acting risk factors in patients with acute ischemic stroke. Protecting oral hygiene may be helpful for SAP prevention.

Key words:

ischemicstroke, oral hygiene, stroke?associated pneumonia, neurological deficit, risk factors, dental caries, aging, activities of daily living