Abstract:

Objective To analyze the risk factors for acute moderate to severe postoperative pain in pa⁃ tients after surgery based on data platform of anesthesiology and perioperative medicine. Methods A total of 1 445 adult patients receiving postoperative continuous intravenous analgesia in our hospital from May 2018 to May 2020 were selected and divided into mild pain cohort（VAS＜4，n=976）and moderate to severe pain cohort（VAS≥4，n= 469）according to visual analogue scale（VAS）score in motion at 24 h after surgery. Twenty⁃one perioperative and intraoperative variables which may relate to postoperative pain of patients in cohort were screened by univariate analysis and multivariate logistic regression to stratify the important risk factors of moderate to severe postoperative pain. Results Univariate analysis showed age，gender，method of anesthesia administration，operation grading， no drinking time，duration of surgery and anesthesia，invasive cannulation，intraoperative infusion，sufentanil and muscle relaxants used during surgery were related to moderate to severe pain（P＜0.05）. Multivariate logistic re⁃ gression analysis showed gender，operation grading，time of prohibition of drinking，dosage of sufentanil and arteri⁃ al catheterization were independent risk factors（P＜0.05）. Conclusion The incidence of postoperative acute moderate to severe pain is related to gender，level of surgical complexity，duration of abstinence from drinking，in⁃ traoperative use of sufentanil and arterial puncture and catheterization，which is worthy of further clinical research.

Key words:

anesthesiology and perioperative medicine, specialized data platform, postoperative pain, risk factors, retrospective study