Abstract:

Objective The study aimed to observe the clinical effect of morphine sulfate sustained⁃release tablets combined with acupuncture on cancer pain. Methods A total of seventy patients with cancer pain admitted to our hospital from January 2020 to June 2021 were randomly divided into control group and observation group. There were 35 cases in each group respectively. The control group was treated with morphine sulfate sustained ⁃ release tablets and the observation group with acupuncture and moxibustion at Zusanli，Baihui and Ashi points. NRS and KPS were applied to evaluate the pain and quality of life. The daily drug use，pain relief rate and incidence of adverse reactions after treatment were analyzed. Results The effective rate in observation group was 91.43%，which was higher than 82.86% in control group（Z = 12.120，P = 0.007）. After treatment，the NRS score and KPS score in observation group were lower than those in control group（P < 0.05）. Compared with the data before treatment，the daily dosage of morphine sulfate sustained ⁃ release tablets in the observation group was basically maintained，while the dosage of drugs in the control group was significantly increased. The incidence of adverse reactions was 48.57% in observation group and 77.14% in control group. Conclusion Acupuncture and moxibustion combined with morphine sulfate sustained⁃release tablets could relieve cancer pain，improve the quality of life of patients，reduce the incidence of adverse reactions and had high safety，which was worthy of clinical promotion.

Key words:

cancer pain, morphine sulfate extended?release tablets, acupuncture, analgesia