The Journal of Practical Medicine ›› 2024, Vol. 40 ›› Issue (15): 2148-2153.doi: 10.3969/j.issn.1006-5725.2024.15.018
• Medical Examination and Clinical Diagnosis • Previous Articles Next Articles
Yue LÜ,Hujing LU,Juanjuan. ZHANG
Received:
2024-02-01
Online:
2024-08-10
Published:
2024-07-30
CLC Number:
Yue LÜ,Hujing LU,Juanjuan. ZHANG. Value of MRI-DWI combined with attenuation imaging in diagnosis of focal nodular lesions < 2 cm in fatty liver[J]. The Journal of Practical Medicine, 2024, 40(15): 2148-2153.
Tab.1
Comparison of clinical data of patients with different focal nodular lesions"
组别 | 例数 | TG(mmol/L) | 年龄(岁) | HDL-C(mmol/L) | 性别[例(%)] | TC(mmol/L) | LDL-C(mmol/L) | |
---|---|---|---|---|---|---|---|---|
男 | 女 | |||||||
良性结节组 | 41 | 2.16 ± 0.33 | 49.87 ± 9.36 | 1.25 ± 0.18 | 24(58.54) | 17(41.46) | 5.43 ± 1.52 | 2.97 ± 0.38 |
恶性结节组 | 27 | 2.22 ± 0.35 | 48.14 ± 9.73 | 1.29 ± 0.17 | 18(66.67) | 9(33.33) | 5.20 ± 1.57 | 2.81 ± 0.42 |
t/χ2值 | 0.716 | 0.734 | 0.916 | 0.456 | 0.603 | 1.629 | ||
P值 | 0.476 | 0.465 | 0.363 | 0.500 | 0.549 | 0.108 |
Tab.2
Comparison of clinical data of patients with different degrees of fatty liver disease"
组别 | 例数 | TG(mmol/L) | 年龄(岁) | HDL-C(mmol/L) | 性别[例(%)] | TC(mmol/L) | LDL-C(mmol/L) | |
---|---|---|---|---|---|---|---|---|
男 | 女 | |||||||
轻度组 | 17 | 2.17 ± 0.32 | 49.72 ± 10.15 | 1.27 ± 0.14 | 10(58.82) | 7(41.18) | 5.41 ± 1.39 | 2.79 ± 0.38 |
中度组 | 27 | 2.23 ± 0.34 | 48.20 ± 9.42 | 1.30 ± 0.16 | 16(59.26) | 11(40.74) | 5.10 ± 1.46 | 2.62 ± 0.34 |
重度组 | 24 | 2.20 ± 0.35 | 49.35 ± 9.98 | 1.29 ± 0.15 | 16(66.67) | 8(33.33) | 5.28 ± 1.32 | 2.68 ± 0.37 |
F/χ2值 | 0.167 | 0.151 | 0.205 | 0.378 | 0.272 | 1.159 | ||
P值 | 0.847 | 0.860 | 0.815 | 0.828 | 0.763 | 0.320 |
Tab.3
Comparison of ADC and AC values in patients with different focal nodular lesions"
组别 | 例数 | ADC值(×10-3mm2/s) | AC值(dB·cm-1·MHz-1) | ||
---|---|---|---|---|---|
b = 100 s/mm2 | b = 500 s/mm2 | b = 1 000 s/mm2 | |||
良性结节组 | 41 | 2.32 ± 0.36 | 2.18 ± 0.27 | 2.11 ± 0.24 | 0.52 ± 0.13 |
恶性结节组 | 27 | 1.78 ± 0.19 | 1.68 ± 0.16 | 1.60 ± 0.15 | 0.97 ± 0.18 |
t值 | 7.153 | 8.660 | 9.835 | 11.970 | |
P值 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Tab.4
Comparison of ADC and AC values in patients with different degrees of fatty liver disease"
组别 | 例数 | ADC值(×10-3mm2/s) | AC值(dB·cm-1·MHz-1) | ||
---|---|---|---|---|---|
b = 100 s/mm2 | b = 500 s/mm2 | b = 1 000 s/mm2 | |||
轻度组 | 17 | 2.06 ± 0.29 | 1.96 ± 0.27 | 1.89 ± 0.25 | 0.59 ± 0.17 |
中度组 | 27 | 1.83 ± 0.23? | 1.78 ± 0.21? | 1.72 ± 0.19? | 0.91 ± 0.24? |
重度组 | 24 | 1.41 ± 0.18?# | 1.35 ± 0.16?# | 1.28 ± 0.12?# | 1.25 ± 0.33?# |
F值 | 42.878 | 47.187 | 51.177 | 32.076 | |
P值 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Tab.5
Analysis of the correlation between ADC and AC values under different b values and the degree of fatty liver disease, TG, HDL-C, TC and LDL-C"
指标 | 脂肪肝病变程度 | TG | HDL-C | TC | LDL-C | |||||
---|---|---|---|---|---|---|---|---|---|---|
r值 | P值 | r值 | P值 | r值 | P值 | r值 | P值 | r值 | P值 | |
ADC值(b = 100 s/mm2) | -0.528 | < 0.001 | -0.082 | 0.543 | 0.128 | 0.361 | 0.320 | 0.414 | 0.074 | 0.453 |
ADC值(b = 500 s/mm2) | -0.571 | < 0.001 | -0.145 | 0.267 | 0.194 | 0.265 | 0.189 | 0.265 | 0.098 | 0.324 |
ADC值(b = 1 000 s/mm2) | -0.494 | < 0.001 | -0.268 | 0.321 | 0.172 | 0.297 | 0.274 | 0.306 | 0.128 | 0.139 |
AC值 | 0.465 | < 0.001 | 0.129 | 0.207 | -0.274 | 0.012 | 0.074 | 0.572 | -0.041 | 0.742 |
Tab.6
Analysis of the diagnostic value of MMRI -DWI combined with AC value in the malignant transformation of fatty liver with focal nodular disease < 2 cm"
指标 | 最佳截断点 | 灵敏度(%) | 特异度(%) | P值 | AUC值 | 95%CI |
---|---|---|---|---|---|---|
MRI-DWI | - | 75.00 | 80.00 | < 0.001 | 0.775 | 0.658 ~ 0.867 |
AC值 | 0.99 dB·cm-1·MHz-1 | 78.57 | 77.50 | < 0.001 | 0.773 | 0.655 ~ 0.866 |
二者联合 | - | 89.29 | 92.50 | < 0.001 | 0.909 | 0.814 ~ 0.965 |
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