急性呼吸窘迫综合征肺纤维化中巨噬细胞和成纤维细胞相互作用的研究进展

doi:10.3969/j.issn.1006-5725.2024.04.023

Abstract

Abstract:

Acute respimtory distress syndrome （ARDS） is an acute diffuse inflammatory lung injury caused by various internal and external lung injury factors. It has complex pathogenesis， rapid onset and high mortality， which seriously endangers human life and health. Pulmonary fibrosis is one of the important pathologic processes of ARDS occurrence and development， and it is also an important cause of death in ARDS patients. To a certain extent， the severity of pulmonary fibrosis in ARDS is determined by the dynamic balance of macrophage-fibroblast interactions. Therefore， this article aims to review the interaction mechanism of macrophage-fibroblasts in the process of ARDS pulmonary fibrosis， and provide new methods and ideas for the diagnosis and treatment of ARDS pulmonary fibrosis.

Key words: acute respiratory distress syndrome, pulmonary fibrosis, macrophage, fibroblasts

CLC Number:

R563

Aiqin LI,Zhen ZHANG,Ya′nan XU,Jinyuan ZHU,Xu. ZHANG. Research progress on the interaction between macro⁃phages and fibroblasts in ARDS pulmonary fibrosis[J]. The Journal of Practical Medicine, 2024, 40(4): 571-574.

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Research progress on the interaction between macro⁃phages and fibroblasts in ARDS pulmonary fibrosis

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