调经助孕合剂联合调经促孕十三针治疗卵泡发育不良型不孕症的效果

doi:10.3969/j.issn.1006-5725.2024.03.023

Abstract

Abstract:

Objective To explore the clinical effects of Tiaojing Zhuyun mixture combined with regulating menstration and promoting pregnancy by thirteen acupuncture in the treatment of Declining Ovarian Function （DOR） combined with follicular dysplasia infertility. Methods From January 1， 2022 to January 1， 2023， 60 cases of infertility patients with DOR follicular dysplasia were treated in our hospital， and the above cases were randomly divided into experimental group： Tiaojing Zhuyun mixture+ regulating menstration and promoting pregnancy by thirteen acupuncture + Clomiphene group； Control group： Clomiphene group， 30 cases each. The improvement of FSH， maximum follicle size and ovulation， uterine artery blood flow index， endometrial thickness and pregnancy were observed after treatment. Results The improvement of follicle stimulating hormone， maximum follicle size， endometrial thickness and uterine artery blood flow indexes in Tiaojing Zhuyun mixture+ regulating menstration and promoting pregnancy by thirteen acupuncture + Clomiphene group were better than clomiphene group. The difference between groups was statistically significant （P < 0.05）. The ovulation rate was 66.7% and the pregnancy rate was 40%. The ovulation rate was 40% higher than the control group， and the pregnancy rate was 20%. The difference between groups was statistically significant （P < 0.05）. Conclusion In the patients with DOR follicular dysplasia infertility， Tiaojing Zhuyun mixture combined with regulating menstration and promoting pregnancy by thirteen acupuncture can improve the level of follicle stimulating hormone， promote follicular maturation and ovulation， reduce the resistance of uterine artery blood flow， increase the thickness of endometrial， promote pregnancy， and have fewer adverse reactions.

Key words: tiaojingzhuyun mixture, regulating menstration and promoting pregnancy by thirteen acupuncture, infertility, decreased ovarian function, follicle dysplasia

CLC Number:

R271.14

Xi CHEN,Xinni WANG,Yuan QI,Shuxiang HU,Jin LI. Effect analysis of combined Tiaojingzhuyun mixture and regulating menstration and promoting pregnancy by thirteen acupuncture in treating infertility caused by Follicle dysplasia[J]. The Journal of Practical Medicine, 2024, 40(3): 412-416.

Figures/Tables 4

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References 29

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组别	例数	排卵率	妊娠率
观察组	30	20（66.7）^*	16（40.0）^a
对照组	30	12（40.0）	7（20.0）
χ ² 值		4.286	5.711
P值		0.001	0.017

组别	例数	治疗前	治疗后	t值	P值
观察组	30	14.267±1.436	18.367±0.765	-14.590	0.008
对照组	30	14.300±1.393	16.567±1.194	-9.283	0.012
t值		-0.252	6.858
P值		0.502	0.002

组别	例数	Em（cm）		PI		RI
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
观察组	30	0.613 ± 0.116	0.897 ± 0.103^?	2.070 ± 0.285	1.407 ± 0.223^?	0.990 ± 0.142	0.549 ± 0.122^?
对照组	30	0.610 ± 0.126	0.637 ± 0.119^?	1.900 ± 0.356	1.577 ± 0.214^?	0.980 ± 0.149	0.750 ± 0.120^?
t值		0.254	9.089	1.649	-3.616	0.551	-7.822
P值		0.801	0.002	0.110	0.001	0.586	0.001

组别	例数	治疗前	治疗后	t值	P值
观察组	30	17.360 ± 5.131	8.845 ± 1.702	9.927	0.004
对照组	30	19.090 ± 3.456	16.747 ± 3.670	11.353	0.012
t值		-2.214	-10.74
P值		0.422	0.003

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Effect analysis of combined Tiaojingzhuyun mixture and regulating menstration and promoting pregnancy by thirteen acupuncture in treating infertility caused by Follicle dysplasia

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