Abstract:

Objective To explore the curative effect of Quick needling combined with Jingshu Granule on cervical vertigo in patients with blood stasis and qi stagnation pattern. Methods A total of 106 cervical vertigo patients with blood stasis and qi stagnation pattern admitted to the hospital from November 2019 to August 2022 were selected and divided into observation group （n = 53） and control group （n = 53） by random number table method. The control group was treated with Jingshu granule， and the observation group was treated with Quick needling combined with Jingshu granule. The effects of continuous treatment for 8 weeks in both groups were observed. TCM syndrome score， vertigo improvement and clinical efficacy were compared between the two groups. The improvement of inflammatory factors， vasomotor factors and vertebrobasilar hemodynamics in peripheral blood was compared between the two groups. The occurrence of adverse reactions during treatment was recorded and compared between the two groups. Results The TCM syndrome scores of the main and secondary symptoms of the two groups after treatment were lower than before treatment （P < 0.05）， and the TCM syndrome scores of the main and secondary symptoms of the observation group after treatment were lower than those of the control group （P < 0.05）. Dizziness handicap inventory （DHI） scores of both groups after treatment were lower than before treatment （P < 0.05）， DHI scores of the observation group were lower than that of the control group after treatment（P < 0.05）. The total effective rate of the observation group was higher than that of the control group （P < 0.05）. After treatment， the tumor necrosis factor-α （TNF-α）， interleukin-6 （IL-6） and C-reactive protein （CRP） in both groups were lower than before treatment （P < 0.05）， and the TNF-α， IL-6 and CRP in the observation group were lower than that of the control group （P < 0.05）. Endothelin-1 （ET-1） and 5-hydroxytryptamine （5-HT） after treatment were lower than before treatment， nitric oxide （NO） was higher than before treatment （P < 0.05）， ET-1 and 5-HT in observation group after treatment were lower than those of the control group， and NO was higher than that of the control group （P < 0.05）. The blood flow velocity of left vertebral artery， right vertebral artery and basilar artery in both groups after treatment was higher than before treatment （P < 0.05）， and the blood flow velocity of left vertebral artery， right vertebral artery and basilar artery in the observation group after treatment was higher than those of the control group （P < 0.05）. There was no obvious adverse reaction in both groups during treatment. Conclusion For the treatment of cervical vertigo patients with blood stasis and qi-stagnation pattern， the combination of Quick needling and Jingshu Granule could enhance clinical efficacy， inhibit the synthesis of inflammatory factors in peripheral blood， improve vasomotor factors and vertebrobasilar hemodynamics， with good safety. It has certain clinical application value.

Key words: cervical vertigo, blood stasis qi stagnation, jingshu granule, quick needling