Abstract:

Objective Retrospective observation of hemodialysis（HD）and peritoneal dialysis（PD）inpatients ESRD with HFpEF compared in dialysis adequacy，electrolytes，nutritional status，the number of re⁃hospi⁃talization due to heart failure and the improvement of New York Heart Association grade at the end of follow⁃up.Methods Clinical data of patients treated with HD and PD in Zhujiang Hospital of Southern Medical Universityfrom January 2010 to June 2019 were collected. The patients with dialysis duration less than 3 months were excluded.The dialysis adequacy，electrolytes，nutritional status，times of re⁃hospitalization due to heart failure and the im⁃provement of New York Heart Association grade were compared between the two groups before the first dialysis andat the end point of follow⁃up. Results There was no significant difference in age，sex，BMI，MAP，heart rate，blood biochemistry and kidney function，NT⁃proBNP，New York Heart association grade and medication betweentwo groups（P > 0.05）. At the end of follow⁃up，the NYHA grade and the number of rehospitalization due to heartfailure in the HD group were significantly lower than those in the CAPD group（P < 0.05）. The levels of serumcreatinine，urea nitrogen and uric acid were decreased significantly in both groups（P＜0.01），but the levels ofserum creatinine and urea nitrogen in HD group were much significantly lower than those in PD group（P < 0.01）.The levels of serum albumin and serum potassium in HD group were significantly higher than those in PD group atthe end of follow⁃up. There was no significant difference in mean arterial pressure and blood lipid between the twogroups（P＞0.05）. Conclusion In this study group，We conclud that the improvement of cardiac function，dialysisadequacy，electrolyte disturbance and nutritional status in the HD group are superior to those in the PD group atthe end of follow⁃up

Key words: heart failure, ejection fraction preserved heart failure, end?stage renal disease, hemodi?alysis, peritoneal dialysis