实用医学杂志 ›› 2023, Vol. 39 ›› Issue (13): 1714-1718.doi: 10.3969/j.issn.1006⁃5725.2023.13.021

• 调查研究 • 上一篇    下一篇

老年高血压人群身高与新发脑梗死关系

郭晓斌1 刘苹2 杨浩辉1 赵景1 阚春娜3 翟婧秀4 于文霞1 赵楚敏1 刘志伟1    

  1. 唐山市第二医院1 内科,4 解剖实验室(河北唐山 063000);2 开滦总医院营养科(河北唐山 063000); 3 唐山市滦南县医院检验科(河北滦南 063500) 
  • 出版日期:2023-07-10 发布日期:2023-07-10
  • 基金资助:
    河北省医学科学研究课题计划项目(编号 :20230233)

The association between the body height and novel cerebral infarction in the elderly with hypertension 

GUO Xiaobin*,LIU Ping,YANG Haohui,ZHAO Jing,KAN Chunna,ZHAI Jingxiu,YU Wenxia,ZHAO Chumin, LIU Zhiwei.   

  1. Department of General Medicine,the Second Hospital of Tangshan,Tangshan 063000,China 
  • Online:2023-07-10 Published:2023-07-10

摘要:

目的 探讨老年高血压人群身高与新发脑梗死的关系。方法 以开滦研究人群为对象,采取前瞻性队列研究方法,纳入 9 574 例老年高血压患者,以首次发生脑梗死为终点事件。依据观察对象身 高值进行四分位分组,用寿命表法分别计算不同身高组累积终点事件发生率,并分别采用 Cox 比例风险模 型分别分析身高对脑梗死风险的影响。结果 在平均(9.3 ± 2.7)年的随访期间内,共新发脑梗死 885 例。 以身高< 161.5 cm(Q1 组)组为对照,多因素 Cox 比例风险回归模型分析显示 161.5 ~ 166.0 cm(Q2 组)、 166.0 ~ 170.0 cm(Q3 组)和≥ 170.0 cm(Q4 组)模型二中新发脑梗死事件风险比[HR(95%CI)]分别为 0.95 (0.78 ~ 1.16)、1.00(0.81 ~ 1.23)、0.71(0.56 ~ 0.90);模型三中各组发生脑梗死 HR 值(95%CI)分别为 1.01 (0.81 ~ 1.24)、1.10(0.89 ~ 1.36)、0.76(0.60 ~ 0.96);模型四中各组发生脑梗死 HR 值(95%CI)分别为 0.98 (0.79 ~ 1.21)、1.06(0.85 ~ 1.33)、0.72(0.56 ~ 0.93)。结论 在老年高血压人群中较高的身高与新发脑梗 死风险降低相关。 

关键词: 身高, 脑梗死, 高血压, 队列研究, 老年人

Abstract:

Objective The study aimed to investigate the association between the body height and the risk of novel cerebral infarction in the elderly with hypertension. Methods 9 574 elderly hypertension patients were monitored in this cohort research based on the Kailuan research group for cerebral infarction. Patients were categorized into quartile groups.The life table method was used to calculate the cumulative incidences of outcomes in different groups. Cox proportional hazards model was used to analyze hazard ratios(HR)with the corresponding 95% confidence interval(CI)of outcomes in different groups. Results Compared to the body height ≤ 161.5 cm (Q1)group,the multivariate Cox proportional hazard regression model showed that the hazard ratio[HR(95%CI)] for cerebral infarction in model 2 were 0.95(0.78 ~ 1.16),1.00(0.81 ~ 1.23)and 0.71(0.56 ~ 0.90) respectively in 161.5 ~ 166.0 cm(Q2),166.0 ~ 170.0 cm(Q3)and ≥ 170.0 cm(Q4);in model 3,cerebral infarction[HR (95%CI)]in each group were 1.01(0.81 ~ 1.24),1.10(0.89 ~ 1.36)and 0.76(0.60 ~ 0.96)respectively;in model 4 were 0.98(0.79 ~ 1.21),1.06(0.85 ~ 1.33)and 0.72(0.56 ~ 0.93),respectively. Conclusion In the elderly with hypertension,a taller body height is connected with a decreased incidence of cerebral infarction.

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