实用医学杂志 ›› 2021, Vol. 37 ›› Issue (15): 1958-1962.doi: 10.3969/j.issn.1006⁃5725.2021.15.010

• 临床研究 • 上一篇    下一篇

基于麻醉与围术期医学专科数据平台的术后急性中重度疼痛风险因素分析

张辉1, 刘德成1 ,王益敏1, 施辰光2, 杨栋2   

  1. 1 广东省第二人民医院麻醉科(广州 510317);2 广州知汇云科技有限公司数据科学部(广州 510000)

  • 出版日期:2021-08-10 发布日期:2021-08-10
  • 基金资助:
     基金项目:广东省医学科学技术研究基金项目(编号:A2020532)

Risk factors analysis for acute moderate to severe postoperative pain based on data platform of anesthesiol⁃ ogy and perioperative medicine

ZHANG Hui* LIU Decheng WANG Yimin SHI Chenguang YANG Dong.   

  1. Department of Anesthesiology,Guangdong Second Provincial General Hospital,Guangzhou 510317,China

  • Online:2021-08-10 Published:2021-08-10

摘要:

目的 基于麻醉与围术期医学专科数据平台,回顾性分析影响术后急性中重度疼痛发生的风险因素。 方法 通过数据平台,筛选 2018 5 月至 2020 5 月在我院行非局麻手术且术后采用连续静 脉镇痛的成年患者 1 445 例,根据术后 24 h 运动 VAS 评分,将患者分成轻度疼痛(VAS < 4 分,n=976)和中重度疼痛(VAS ≥ 4 分,n=469)两组,筛选所有患者术前、术中和术后疼痛发生具有一定相关性指标共 21 项,采用单因素及多因素 logistics 回归方法分析与术后中重度疼痛发生相关的风险因素。 结果 单因素分析显示术后轻度疼痛和中重度疼痛两组年龄、性别、麻醉方法、手术级别、禁饮时间、手术麻醉时间、有创监测操作、补液量及术中舒芬太尼和肌松药物使用差异有统计学意义(P < 0.05),多因素 logistics 回归分析显示性别、手术级别、禁饮时间、术中舒芬太尼使用和动脉穿刺置管是影响术后急性中重度疼痛的独立危险因素(P < 0.05)。 结论 术后急性中重度疼痛发生与性别、手术级别、禁饮时间、术中舒芬太尼使用和动脉穿刺置管有关,值得临床大数据研究参考。

关键词:

麻醉与围术期医学, 数据平台, 术后疼痛, 危险因素, 回顾性研究

Abstract:

Objective To analyze the risk factors for acute moderate to severe postoperative pain in pa⁃ tients after surgery based on data platform of anesthesiology and perioperative medicine. Methods A total of 1 445 adult patients receiving postoperative continuous intravenous analgesia in our hospital from May 2018 to May 2020 were selected and divided into mild pain cohort(VAS<4,n=976)and moderate to severe pain cohort(VAS≥4,n= 469)according to visual analogue scale(VAS)score in motion at 24 h after surgery. Twenty⁃one perioperative and intraoperative variables which may relate to postoperative pain of patients in cohort were screened by univariate analysis and multivariate logistic regression to stratify the important risk factors of moderate to severe postoperative pain. Results Univariate analysis showed age,gender,method of anesthesia administration,operation grading no drinking time,duration of surgery and anesthesia,invasive cannulation,intraoperative infusion,sufentanil and muscle relaxants used during surgery were related to moderate to severe pain(P<0.05). Multivariate logistic re⁃ gression analysis showed gender,operation grading,time of prohibition of drinking,dosage of sufentanil and arteri⁃ al catheterization were independent risk factors(P<0.05). Conclusion The incidence of postoperative acute moderate to severe pain is related to gender,level of surgical complexity,duration of abstinence from drinking,in⁃ traoperative use of sufentanil and arterial puncture and catheterization,which is worthy of further clinical research.

Key words:

anesthesiology and perioperative medicine, specialized data platform, postoperative pain, risk factors, retrospective study