The Journal of Practical Medicine ›› 2021, Vol. 37 ›› Issue (12): 1516-1519.doi: 10.3969/j.issn.1006⁃5725.2021.12.002

• Clinical Advances • Previous Articles     Next Articles

Role of immune checkpoint inhibitors in treatment of advanced prostate cancer:A literature review 

YI Chufan,FU Weijin.   

  1. Department of Urology,the First Affiliated Hospital of Guangxi Medical University,Nanning 530022,China 

  • Online:2021-06-25 Published:2021-06-25
  • Contact: FU Weijin E⁃mail:fuwj666@aliyun.com

Abstract:

Prostate cancer(PCa)is most common among American and European males. Advanced PCa patients are witnessed to be effectively treated with androgen deprivation therapy(ADT)at the preliminary stage and it eventually develops to the castration⁃resistant prostate cancer(CRPC),which results in poor prognosis. In recent years,immune checkpoint inhibitors(ICIs)have been successfully applied in the treatment of advanced PCa. In this paper,we have reviewed the literature on ICIs′ role in the treatment of advanced PCa,and discussed its development directions and application prospects.

Key words:

immune checkpoint inhibitors, prostate cancer, therapy