The Journal of Practical Medicine ›› 2025, Vol. 41 ›› Issue (10): 1439-1444.doi: 10.3969/j.issn.1006-5725.2025.10.002
• Comments • Previous Articles Next Articles
Zheng ZHANG,Yun MENG,Yuanyuan. WANG()
Received:
2025-02-19
Online:
2025-05-25
Published:
2025-05-21
Contact:
Yuanyuan. WANG
E-mail:angelayuanyuanwang@gmail.com
CLC Number:
Zheng ZHANG,Yun MENG,Yuanyuan. WANG. Application, development, and challenges of digital therapeutics in interventions for adolescent social anxiety disorder[J]. The Journal of Practical Medicine, 2025, 41(10): 1439-1444.
1 |
SALARI N, HEIDARIAN P, HASSANABADI M, et al. Global prevalence of social anxiety disorder in children, adolescents and youth: A systematic review and meta-analysis[J]. J Prev, 2024, 45(5): 795-813. doi:10.1007/s10935-024-00789-9
doi: 10.1007/s10935-024-00789-9 |
2 |
JIN Y, WARMENHOVEN H, XU S, et al. Childhood abuse and social anxiety: Socio-demographic correlates of social anxiety disorder among male and female youth exposed to childhood abuse[J]. Curr Psychol, 2024, 43(6): 5206-5218. doi:10.1007/s12144-023-04711-0
doi: 10.1007/s12144-023-04711-0 |
3 |
YU H, XU S, LI H, et al. A man-made divide: Investigating the effect of urban–rural household registration and subjective social status on mental health mediated by loneliness among a large sample of university students in china[J]. Front Psychol, 2022, 13: 1012393. doi:10.3389/fpsyg.2022.1012393
doi: 10.3389/fpsyg.2022.1012393 |
4 |
LI J, JIN Y, XU S, et al. Anxiety and depression symptoms among youth survivors of childhood sexual abuse: A network analysis[J]. BMC Psychol, 2023, 11(1): 278. doi:10.1186/s40359-023-01275-3
doi: 10.1186/s40359-023-01275-3 |
5 |
LI J, JIN Y, XU S, et al. Effects of bullying on anxiety, depression, and posttraumatic stress disorder among sexual minority youths: Network analysis[J]. JMIR Public Health Surveill, 2023, 9: e47233. doi:10.2196/47233
doi: 10.2196/47233 |
6 |
JIN Y, XU S, SHAO Z, et al. Discovery of depression-associated factors among childhood trauma victims from a large sample size: Using machine learning and network analysis[J]. J Affect Disord, 2024, 345: 300-310. doi:10.1016/j.jad.2023.10.101
doi: 10.1016/j.jad.2023.10.101 |
7 |
JIN Y, LI J, YE J, et al. Mapping associations between anxiety and sleep problems among outpatients in high-altitude areas: A network analysis[J]. BMC Psychiatry, 2023, 23(1): 341. doi:10.1186/s12888-023-04767-z
doi: 10.1186/s12888-023-04767-z |
8 |
ALVES F, FIGUEIREDO D V, VAGOS P. The prevalence of adolescent social fears and social anxiety disorder in school contexts[J]. Int J Environ Res Public Health, 2022, 19(19): 12458. doi:10.3390/ijerph191912458
doi: 10.3390/ijerph191912458 |
9 |
VAN BALLEGOOIJEN W, CUIJPERS P, VAN STRATEN A, et al. Adherence to internet-based and face-to-face cognitive behavioural therapy for depression: A meta-analysis[J]. PLoS One, 2014, 9(7): e100674. doi:10.1371/journal.pone.0100674
doi: 10.1371/journal.pone.0100674 |
10 |
PATEL V. Mental health in low- and middle-income countries[J]. Br Med Bull, 2007, 81-82: 81-96. doi:10.1093/bmb/ldm010
doi: 10.1093/bmb/ldm010 |
11 |
FRSTENAU D, GERSCH M, SCHREITER S. Digital therapeutics (dtx)[J]. Bus Inf Syst Eng, 2023, 65(3): 349-360. doi:10.1007/s12599-023-00804-z
doi: 10.1007/s12599-023-00804-z |
12 |
HYSING M, PALLESEN S, STORMARK K M, et al. Sleep and use of electronic devices in adolescence: Results from a large population-based study[J]. BMJ Open, 2015, 5(1): e006748. doi:10.1136/bmjopen-2014-006748
doi: 10.1136/bmjopen-2014-006748 |
13 |
CHOI S H, SHIN J E, KU J, et al. Looking at the self in front of others: Neural correlates of attentional bias in social anxiety[J]. J Psychiatr Res, 2016, 75: 31-40. doi:10.1016/j.jpsychires.2016.01.001
doi: 10.1016/j.jpsychires.2016.01.001 |
14 |
YIN F, SI F, HUO S H, et al. Social anxiety modulating early processing for social threat words: An erp study[J]. Cogn Emot, 2024: 1-11. doi:10.1080/02699931.2024.2381660
doi: 10.1080/02699931.2024.2381660 |
15 |
CHEN Y, YANG X, ZHANG X, et al. Altered single-subject gray matter structural networks in social anxiety disorder[J]. Cereb Cortex, 2023, 33(6): 3311-3317. doi:10.1093/cercor/bhac498
doi: 10.1093/cercor/bhac498 |
16 |
GELLNER A K, VOELTER J, SCHMIDT U, et al. Molecular and neurocircuitry mechanisms of social avoidance[J]. Cell Mol Life Sci, 2021, 78(4): 1163-1189. doi:10.1007/s00018-020-03649-x
doi: 10.1007/s00018-020-03649-x |
17 |
SKHIRTLADZE N, VAN PETEGEM S. Perceived overprotective parenting and identity synthesis and confusion in georgian emerging adults: The intervening role of goal engagement and disengagement[J]. J Adult Dev, 2025,32:1-11. doi:10.1007/s10804-024-09475-w
doi: 10.1007/s10804-024-09475-w |
18 |
ZHANG B F, ZHANG X Y. Correlation between self-efficacy, parental parenting patterns, and severe depression in adolescents[J]. World J Psychiatry, 2024, 14(12): 1827-1835. doi:10.5498/wjp.v14.i12.1827
doi: 10.5498/wjp.v14.i12.1827 |
19 |
CARTER R, HALAWAH A, TRINH S L. Peer exclusion during the pubertal transition: The role of social competence[J]. J Youth Adolesc, 2018, 47(1): 121-134. doi:10.1007/s10964-017-0682-8
doi: 10.1007/s10964-017-0682-8 |
20 |
LACOMBE C, ELALOUF K, COLLIN C. Impact of social anxiety on communication skills in face-to-face vs. Online contexts[J]. Comput Human Behav Rep, 2024, 15(7): 100458. doi:10.1016/j.chbr.2024.100458
doi: 10.1016/j.chbr.2024.100458 |
21 |
MORINA N, KAMPMANN I, EMMELKAMP P, et al. Meta-analysis of virtual reality exposure therapy for social anxiety disorder[J]. Psychol Med, 2023, 53(5): 2176-2178. doi:10.1017/s0033291721001690
doi: 10.1017/s0033291721001690 |
22 |
WONG K P, LAI C Y Y, QIN J. Systematic review and meta-analysis of randomised controlled trials for evaluating the effectiveness of virtual reality therapy for social anxiety disorder[J]. J Affect Disord, 2023, 333: 353-364. doi:10.1016/j.jad.2023.04.043
doi: 10.1016/j.jad.2023.04.043 |
23 |
张正,蒋正乾,刘佳丽,等. 数字疗法在精神疾病诊疗中的发展[J]. 实用医学杂志,2024,40(18):2513-2519. doi:10.3969/j.issn.1006-5725.2024.18.001
doi: 10.3969/j.issn.1006-5725.2024.18.001 |
24 |
HEATHCOTE L C, CUNNINGHAM S J, WEBSTER S N, et al. Smartphone-based ecological momentary assessment to study "scanxiety" among adolescent and young adult survivors of childhood cancer: A feasibility study[J]. Psychooncology, 2022, 31(8): 1322-1330. doi:10.1002/pon.5935
doi: 10.1002/pon.5935 |
25 | YEHUDA C B, GILAD-BACHRACH R, UDI Y. Improving engagement and efficacy of mhealth micro-interventions for stress coping: An in-the-wild study[DB/OL]. (2024-07-16)[2025-02-19]. . |
26 |
AMER N A, SHOHIEB S M, ELADROSY W, et al. A gamified cognitive behavioral therapy for arabs to reduce symptoms of depression and anxiety: A case study research[J]. Digit Health, 2024, 10. doi:10.1177/20552076241263317
doi: 10.1177/20552076241263317 |
27 |
LEPE-SALAZAR F, GARCíA-MICHEL S. Game-based prevention of social anxiety in young people[C].2023 IEEE International Conference on E-health Networking, Application & Services (Healthcom). Chongqing, China, 2023: 19-25. doi:10.1109/healthcom56612.2023.10472360
doi: 10.1109/healthcom56612.2023.10472360 |
28 |
NAWAZ F A, MOTTERSHEAD R, FAROOQ R, et al. Integrating metaverse in psychiatry for adolescent care and treatment (impact)[J]. Digit Health, 2024, 10:20552076241297055. doi:10.1177/20552076241297055
doi: 10.1177/20552076241297055 |
29 | PAULEY D, CUIJPERS P, PAPOLA D, et al. Two decades of digital interventions for anxiety disorders: A systematic review and meta-analysis of treatment effectiveness[J]. Psychol Med, 2023, 53(2): 567-579. |
30 |
HAMILTON J P, FOGELMAN P, GOTLIB I. Depressive rumination, the default-mode network, and the dark matter of clinical neuroscience[J]. Biol Psychiatry, 2015, 78(4): 224-230. doi:10.1016/j.biopsych.2015.02.020
doi: 10.1016/j.biopsych.2015.02.020 |
31 |
GODDINGS A L, ROALF D, LEBEL C, et al. Development of white matter microstructure and executive functions during childhood and adolescence: A review of diffusion mri studies[J]. Dev Cogn Neurosci, 2021, 51: 101008. doi:10.1016/j.dcn.2021.101008
doi: 10.1016/j.dcn.2021.101008 |
32 |
NITTAS V, DANIORE P, CHAVEZ S J, et al. Challenges in implementing cultural adaptations of digital health interventions[J]. Commun Med, 2024, 4(1): 7. doi:10.1038/s43856-024-00479-x
doi: 10.1038/s43856-024-00479-x |
33 |
WEISE T, PéREZ-TORO P A, DEITERMANN A, et al. Multi-modal biomarker extraction framework for therapy monitoring of social anxiety and depression using audio and video[C]//MAIER A K, SCHNABEL J A, TIWARI P, et al. Machine Learning for Multimodal Healthcare Data. Cham: Springer, 2024: 26-42. doi:10.1007/978-3-031-47679-2_3
doi: 10.1007/978-3-031-47679-2_3 |
34 |
JIN Y, XU S C, CHEN C, et al. Symptom association between social anxiety disorder, appearance anxiety, and eating disorders among chinese university students: A network analysis to conceptualize comorbidity[J]. Front Public Health, 2022, 10:1044081. doi:10.3389/fpubh.2022.1044081
doi: 10.3389/fpubh.2022.1044081 |
35 |
KIM B, NIU X, ZHANG F. Functional connectivity strength and topology differences in social phobia adolescents with and without adhd comorbidity[J]. Neuropsychologia, 2023, 178: 108418. doi:10.1016/j.neuropsychologia.2022.108418
doi: 10.1016/j.neuropsychologia.2022.108418 |
36 |
KOYUNCU A, ERTEKIN E, YUKSEL C, et al. Predominantly inattentive type of adhd is associated with social anxiety disorder[J]. J Atten Disord, 2015, 19(10): 856-864. doi:10.1177/1087054714533193
doi: 10.1177/1087054714533193 |
37 |
NEIGE C, IMBERT L, BEYNEL L, et al. Dual activation of the reward system using sensory-based intervention and non-invasive brain stimulation in depression: A way to move forward?[J]. Med Hypotheses, 2024, 189: 111403. doi:10.1016/j.mehy.2024.111403
doi: 10.1016/j.mehy.2024.111403 |
38 |
张正,程博皓,蒋正乾,等. 构建青少年抑郁自杀风险监测与防治的多学科多主体协作模式[J]. 中华精神科杂志,2024,57(1):12-17. doi:10.3760/cma.j.cn113661-20231026-00157
doi: 10.3760/cma.j.cn113661-20231026-00157 |
39 | 曾泳添,陈日玲,农雪艳,等. 数字疗法在自闭症筛查到干预的临床研究进展与挑战[J]. 中国全科医学,2025,28(14):1702-1708. |
40 | VU H, NGUYEN H, GANESAN A V, et al. Psychadapter: Adapting llm transformers to reflect traits, personality and mental health[DB/OL](2025-01-01)[2025-02-19]. . |
41 |
PETRIGNA L, MUSUMECI G. The metaverse: A new challenge for the healthcare system: A scoping review[J]. J Funct Morphol Kinesiol, 2022, 7(3): 63. doi:10.3390/jfmk7030063
doi: 10.3390/jfmk7030063 |
42 |
USMANI S S, SHARATH M, MEHENDALE M. Future of mental health in the metaverse[J]. Gen Psychiatr, 2022, 35(4): e100825. doi:10.1136/gpsych-2022-100825
doi: 10.1136/gpsych-2022-100825 |
43 |
VICARIO C, SALEHINEJAD M A, LUCIFORA C, et al. Combining virtual reality exposure therapy with non-invasive brain stimulation for the treatment of post-traumatic stress disorder and related syndromes. A perspective[M]//PINNA G. Translational Methods for PTSD Research. New York: Humana, 2023: 231-245. doi:10.1007/978-1-0716-3218-5_12
doi: 10.1007/978-1-0716-3218-5_12 |
44 |
PREMKUMAR P, HEYM N, MYERS J A C, et al. Augmenting self-guided virtual-reality exposure therapy for social anxiety with biofeedback: A randomised controlled trial[J]. Front Psychiatry, 2024, 15:1467141. doi:10.3389/fpsyt.2024.1467141
doi: 10.3389/fpsyt.2024.1467141 |
45 |
JIN Y, WARMENHOVEN H, XU S C, et al. Childhood abuse and social anxiety: Socio-demographic correlates of social anxiety disorder among male and female youth exposed to childhood abuse[J]. Curr Psychol, 2024, 43(6): 5206-5218. doi:10.1007/s12144-023-04711-0
doi: 10.1007/s12144-023-04711-0 |
46 | 安宇坤,王晨希. 数字疗法的应用、审批监管现状及展望[J].中国医疗器械信息,2024,30(15):13-16. |
47 | 孟可强,王丽,李旺,等. 构建乡村社会心理服务体系助力乡村振兴战略[J]. 中国科学院院刊,2023,38(3):444-454. |
48 |
STEIN O A, PROST A. Exploring the societal implications of digital mental health technologies: A critical review[J]. SSM Ment Health, 2024, 6: 100373. doi:10.1016/j.ssmmh.2024.100373
doi: 10.1016/j.ssmmh.2024.100373 |
[1] | Yingmei HAN,Yijie LI,Heng ZHANG,Weiqing LI,Ze FENG,Feng WANG. The application value of deep learning in imaging studies for predicting the conversion of Alzheimer′s disease [J]. The Journal of Practical Medicine, 2025, 41(9): 1413-1424. |
[2] | Rui GUO,Tao LIU,Xi. SU. Establishment of a nomogram model for comorbid cardiovascular disease in schizophrenia based on electrocardiogram parameters and kynurenine metabolites [J]. The Journal of Practical Medicine, 2025, 41(8): 1205-1211. |
[3] | Tianyue YU,Qian GUO,Hao HU,Yujing SU,Jianhua CHEN. Advances in oxidative stress⁃related pathways with diagnostic and predictive value in schizophrenia [J]. The Journal of Practical Medicine, 2024, 40(20): 2935-2940. |
[4] | Zheng ZHANG,Zhengqian JIANG,Jiali LIU,Xia CAO,Jiansong. ZHOU. Development of digital therapy in the diagnosis and treatment of psychiatric disorders [J]. The Journal of Practical Medicine, 2024, 40(18): 2513-2519. |
[5] | Zhiyan XU,Weiyuan CHEN,Weifeng. YAO. Mechanism and research progress of dexmedetomidine in improving perioperative neurocognitive disorder in frail elderly patients [J]. The Journal of Practical Medicine, 2024, 40(17): 2503-2507. |
[6] | . [J]. The Journal of Practical Medicine, 2024, 40(12): 1677-1682. |
[7] | Qiaofang HUANG,Xingxiao HUANG,Junyi LIN,Lian DUAN,Zhentai PANG,Shaojuan WU,Caimei ZOU,Shichao XU. Effect of physician⁃nurse⁃social worker linkage rehabilitation model on psychological status in patients receiving methadone maintenance treatment [J]. The Journal of Practical Medicine, 2024, 40(9): 1238-1243. |
[8] | Bing LIU,Hanxi CHEN,Wenji LIU,Yingwen HUANG,Yan WANG,Chan HUANG,Tianhui. YOU. Impacts of illness perception and coping style on social participation in patients receiving surgery for Stanford type A aortic dissection [J]. The Journal of Practical Medicine, 2024, 40(8): 1160-1166. |
[9] | Shuangyan LI,Bin ZHANG. Research status and challenges of insomnia disorder [J]. The Journal of Practical Medicine, 2024, 40(6): 731-737. |
[10] | Xilin WANG,Chanjuan YANG,Daomeng. CHENG. Construction of a nomogram prediction model for aggressive behavior in patients with bipolar disorder [J]. The Journal of Practical Medicine, 2024, 40(5): 677-681. |
[11] | Rui XU,Xingbing. HUANG. Progress of non-pharmacological treatments for treatment-resistant depression [J]. The Journal of Practical Medicine, 2024, 40(4): 439-446. |
[12] | Yonghui LIU,Qingjing TAN,Qing CHEN,Liping WEI,Junwei YANG,Kan YANG,Yuguang. GAO. The mechanism of target regulating of miR⁃421 to Menin/Caspase⁃3 pathway for depression [J]. The Journal of Practical Medicine, 2024, 40(4): 453-459. |
[13] | Li LI,Lin. TANG. Analysis of influencing factors of non⁃suicidal self⁃injury behavior and motivation in adult patients with depression [J]. The Journal of Practical Medicine, 2024, 40(4): 466-470. |
[14] | Xia NAN,Wenling LI,Lin. WANG. Advances in MRI studies of brain structure and cerebral blood perfusion in patients with bipolar disorder [J]. The Journal of Practical Medicine, 2024, 40(4): 580-584. |
[15] | Yanlin LIU,Hui LI,Xiaoliang. ZHOU. Effects of different doses of sodium valproate on serum TSH, PRL and DA levels in patients with bipolar disorder [J]. The Journal of Practical Medicine, 2024, 40(1): 97-101. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||