双相情感障碍患者脑结构及脑血流灌注的MRI研究进展

doi:10.3969/j.issn.1006-5725.2024.04.025

Abstract

Abstract:

Bipolar disorder （BD） is a class of common psychiatric disorders， and its high morbidity， disability， and mortality have attracted widespread attention. However， in clinical practice， the initial accurate diagnosis rate of BD is low and easily misdiagnosed as monophasic depression. Many neuroimaging studies have shown that cortical thickness， gray matter， white matter， and functional activities are altered in some brain regions of BD patients. However， their specific neuroimaging indexes have not been clarified， and the specific pathophysiological mechanisms for the onset of BD have not been fully elucidated. Therefore， in this paper， we combed through the recent years of BD patients to study the cortical structure and perfusion of the brain to review the methods in anticipation of more in-depth research at a later stage.

Key words: bipolar disorder, MRI, voxel-based morphometry, surface-based morphometry, diffusion tensor imaging, arterial Spin Labeling, SPECT, PET-CT

CLC Number:

R749.4⁺1

Xia NAN,Wenling LI,Lin. WANG. Advances in MRI studies of brain structure and cerebral blood perfusion in patients with bipolar disorder[J]. The Journal of Practical Medicine, 2024, 40(4): 580-584.

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Advances in MRI studies of brain structure and cerebral blood perfusion in patients with bipolar disorder

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