The Journal of Practical Medicine ›› 2024, Vol. 40 ›› Issue (22): 3251-3255.doi: 10.3969/j.issn.1006-5725.2024.22.022

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Research progress of S100A9 in renal diseases

Kunyuan HUANG1,Kehua JIANG2,Qing WANG2()   

  1. *.Department of Urology,Xingyi People's Hospital,Xingyi 562400,Guizhou,China
  • Received:2024-01-31 Online:2024-11-25 Published:2024-11-25
  • Contact: Qing WANG E-mail:wangqing1@gz5055.com

Abstract:

S100A9 is an important alarmin in vivo, which plays a role in regulating inflammation and tumorigenesis. Recently, many studies have also explored the biological function and related mechanism of S100A9 in renal diseases, including acute kidney injury, chronic kidney disease, renal stone, renal transplantation, renal tumor, renal cyst, and urinary infection. They pointed out the potential role of S100A9 as a new diagnostic and therapeutic biomarker for renal diseases. In the current study, we conduct a review of these findings and summarize possible future study directions, which aims to help people understand the impact of S100A9 on renal diseases.

Key words: S100A9, acute kidney injury, chronic kidney disease, kidney stone, kidney transplantation, renal tumor, urinary infection

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