The Journal of Practical Medicine ›› 2024, Vol. 40 ›› Issue (19): 2801-2805.doi: 10.3969/j.issn.1006-5725.2024.19.023

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Advancements in the investigation of cardiovascular risk associated with idiopathic inflammatory myopathy

Xianghong CHEN,Xiumin CHEN,Yingyan ZHOU,Li LI,Zhenxiong. XU()   

  1. The Second Clinical Medical College Affiliated to Guangzhou University of Chinese Medicine,Guangzhou 510405,Guangdong,China
  • Received:2024-04-10 Online:2024-10-10 Published:2024-10-22
  • Contact: Zhenxiong. XU E-mail:xuzhenxiongershi@163.com

Abstract:

The idiopathic inflammatory myopathies encompass a diverse array of autoimmune diseases, characterized by muscular inflammation and various extramuscular manifestations. These conditions have the potential to impact multiple organs, including the lungs, skin, joints, gastrointestinal tract, and heart. The defining features of these conditions are muscle weakness and myalgia. Although cardiac involvement is infrequent, its clinical manifestations are subtle and easily overlooked. Cardiac damage represents a significant contributor to mortality and morbidity in patients with idiopathic inflammatory myopathy. Early and accurate identification of cardiac involvement may facilitate improved patient outcomes. This article provides an overview of the potential etiology, clinical presentations, risk factors, biomarkers, and imaging studies for early diagnosis of cardiac involvement in idiopathic inflammatory myopathy. This review aims to enhance clinicians' understanding and diagnostic capabilities regarding cardiac involvement in idiopathic inflammatory myopathy while promoting early intervention strategies for lifelong management and improved prognosis.

Key words: idiopathic inflammatory myopathy, cardiovascular risk, risk factors

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