高脂饮食引发胃肠菌群改变与胃肠肿瘤关系的研究进展

doi:10.3969/j.issn.1006-5725.2024.01.022

Abstract

Abstract:

In healthy individuals， there is a favourable balance between commensal and potentially pathogenic bacteria. When the balance is broken， the host might suffer from gastrointestinal cancer. Studies have shown that high-fat diet can alter the composition of gastrointestinal microbiota，gastrointestinal microbiota may promote gastrointestinal cancer by affecting metabolites of gastrointestinal microbiota， leading to loss of gastrointestinal barrier function， suppressing anti-tumor immunity， etc. In this work， we will summary the current knowledge on relations and possible mechanisms of high-fat diet-associated gastrointestinal microbiota and gastrointestinal cancer. To provide new ideas for the treatment of gastrointestinal cancer.

Key words: high fat diet, gastrointestinal microbiota, gastrointestinal cancer

CLC Number:

R589

Qi WU,Le BU,Bei. XU. Research progress of the relationship between high fat diet-Induced gastrointestinal microbiota and gastrointestinal cancer[J]. The Journal of Practical Medicine, 2024, 40(1): 123-128.

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Research progress of the relationship between high fat diet-Induced gastrointestinal microbiota and gastrointestinal cancer

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