Abstract:

Objective By evaluating the correlation of chinese visceral adipose index （CVAI） and obesity-related evaluation indexes with Obstructive sleep apnea（OSA） and analyzing the influencing factors， we aim to screen out the diagnostic indexes of OSA in obesity and evaluate their diagnostic value. Methods A total of 460 obese patients admitted to bariatric surgery were enrolled，they were divided into OSA group and non-OSA group according to apnea hypopnea index （AHI）， All subjects were measured for height， weight， neck circumference（NC）， waist circumference（WC） and hip circumference（HC）， examined for lipid levels， BMI， waist-to-height ratio（WHtR）， waist-to-hip ratio（WHR） and CVAI were calculated according to the formula， The correlation between these indexes and AHI was analyzed and the influencing factors of OSA were screened out， The diagnostic value was evaluated by receiver operating characteristic curve （ROC） analysis. Results The prevalence of OSA in this study was 62%， Body weight， BMI， NC， WC， HC， WHtR， CVAI and AHI in OSA group were higher than those in non-OSA group， The lowest oxygen saturation and average oxygen saturation were lower than those in non-OSA group （P < 0.05）. BMI， NC， WC，HC， WHtR， WHR， CVAI were positively correlated with AHI， and the correlation between NC and AHI was the strongest， followed by CVAI. Gender， NC and CVAI were independent influencing factors of OSA.ROC curve analysis showed that the area under curve （AUC） of NC and CVAI were 0.627 and 0.652 respectively.The critical value of NV for male was 47.75 cm， with 64.1% sensitivity and 78.9% specificity， The optimal threshold value for female was 39.75 cm， the sensitivity was 70.6%， the specificity was 51.8%； The critical value of CVAI for male was 266.19， with 67.2% sensitivity and 68.4% specificity， and the optimal critical value for female was 170.54， with 59.7% sensitivity and 75.9% specificity.The AUC value of the combined diagnosis was 0.653， higher than that of the single index， with 73.7% sensitivity and 53.7% specificity. Conclusion CVAI is closely correlated with OSA in obese patients， and can be used as a predictor of OSA in obese patients， the predictive value was higher when combined with NC.

Key words: chinese visceral adipose index, obesity, obstructive sleep apnea