Abstract:

Objective To study the effect of drug eluting balloon combined with cutting balloon after coro⁃ nary artery stenting. Methods In this prospective study，we included 72 patients contracting in ⁃stent restenosis （ISR）with a stenosis rate ≥ 50% after coronary artery stenting hospitalized in our hospital during July 2021 and December 2021 and divided them equally into observation group and control group. The patients in the observation group were treated with drug⁃eluting balloon joint cutting balloon and those in the control group with drug eluting balloon. The two groups were compared in terms of treatment effect，cardiac function and adverse cardiovascular events. Results After treatment，the vascular inner diameter and the stenosis rate among the patients in the two groups were significantly improved（P < 0.05）. The vascular inner diameter in the observation group was signifi⁃ cantly larger than that in the control group（P < 0.05）and the stenosis rate was significantly lower than that in the control group（P < 0.05）. After treatment，the LVEF and LAD in the two groups were significantly increased（P < 0.05），while RVD，LVD and LVEDV were decreased（P < 0.05）. The LVEF and LAD in the observation group were significantly higher than those in the control group（P < 0.05）and RVD，LVD and LVEDV were significantly lower than those of the control group（P < 0.05）. The incidences of recurrent angina pectoris，non⁃fatal myocardial infarction，target vessel revascularization and heart failure in the observation group at 6 months after operation were significantly lower than those in the control group（P < 0.05）. The postoperative Mb and cTn Ⅰ in the observation group were significantly higher than those in the control group（P < 0.05）. There was no significant difference in the levels of Mb and cTn Ⅰ between the two groups 6 months after operation（P > 0.05）. Conclusion For treating patients with ISR，cutting balloon combined with drug eluting balloon achieves good therapeutic effect and prognosis.

Key words:

coronary stent implantation, cutting balloon, drug elution balloon, adverse cardiovascu? lar events ,