Abstract:

Objective To explore the clinical value of betahistine combined with vestibular training for residual symptoms of benign paroxysmal positional vertigo （BPPV）following manipulative reduction. Methods 160 BPPV patients with residual symptoms in our hospital from January 2018 to December 2019 were randomly divided into a control group（79 patients）and a study group（81 patients）. The control group received routine vestibular training alone，whereas the study group received betahistine in addition to vestibular training for 2 months. Visual analogue scale（VAS），frequency of residual symptoms，scores on dizziness disorder scale（DHI），and adverse reactions were compared between the two groups before and after treatment. Results Before treatment， there were no significant differences between the two groups in the total scores on DHI physical disorder（DHIP）， DHI emotional disorder（DHIE），DHI dysfunction（DHIF）and DHI（t = 0.228，0.054，0.193 and 0.267；P > 0.05）. After treatment，the total scores on DHIP，DHIE，DHIF and DHI were lower in the study group than in the control group（t = 17.051，8.267，8.644 and 19.449；P < 0.05）. Before treatment，there was no significant difference in the VAS score of vertigo between the two groups（t = 0.234，P > 0.05）. After treatment，the VAS score of vertigo in the study group was lower than that in the control group（t = 13.583，P < 0.05）. The frequency of walking instability， floating feeling，drowsiness，and dizziness was lower in the study group than in the control group（t = 15.915， 14.748，11.004 and 8.350；P < 0.05）；There was no significant difference in the rate of adverse reactions between the two groups（χ2 = 0.231，P > 0.05）. Conclusions Vestibular training combined with betahistine can effectively reduce the degree of vertigo disorder and lower the frequency of residual symptoms in BPPV patients after manual reduction.

Key words:

 , benign paroxysmal positional vertigo, vestibular training, residual symptoms, betahistine