Abstract:

Objective To investigate the association of mean platelet volume to lymphocyte ratio（MPVLR） with long ⁃ term mortality in patients with coronary heart disease after percutaneous coronary intervention（PCI）. Methods From January 2013 to December 2017，3 472 patients with coronary heart disease undergoing PCI in our hospital were enrolled. Based on receiver operating characteristics curve analysis，the best threshold value for predicting long⁃term mortality in patients with coronary heart disease after PCI was 5.69. According to the threshold value，the patients were divided into the low MPVLR（MPVLR < 5.69，n = 2 433）and the high MPVLR group （MPVLR ≥ 5.69，n = 1 039）. Results Inunivariate analysis，there was a significant difference in all⁃cause death and cardiogenic death between the two groups（P < 0.05）；Cox multivariate regression analysis showed that higher MPVLR level in admission was an independent risk factor for long⁃term cardiogenic death（HR = 1.630，95%CI： 1.020 ~ 2.640，P < 0.05）and all⁃cause death（HR = 1.579，95%CI：1.093 ~ 2.281，P < 0.05）in patients with coronary heart disease after PCI. Conclusions MPVLR has certain predictive value for long⁃term death events in patients with coronary heart disease after PCI.

Key words: