Abstract:

Objective To investigate the difference of lung function and serum cytokine levels in elderly patients diagnosed with COPD with different BMI with acute exacerbation. To analyze the relationship between BMI and lung function and the level of serum cytokine expression. Methods A total of 97 elderly patients with acute exacerbation of COPD admitted to our hospital from June 2018 to December 2019 were selected as the research objects. They were divided into three groups according to BMI：normal body reconstitution（31 cases），low body reconstitution（32 cases），and high body reorganization（34 cases）. The serum cytokine levels，blood gas indexes and lung function indexes of all subjects were determined. Pearson correlation was used to analyze the correlation between BMI and lung function and serum cytokine levels in elderly patients with acute exacerbation of COPD. Results BMI was negatively correlated with serum cytokine levels in elderly patients with acute exacerbation of COPD and positively correlated with lung function. Conclusion BMI is correlated with pulmonary function and inflammatory response index in elderly patients with acute exacerbation of COPD，which can evaluate the severity of the disease to a certain extent.

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