实用医学杂志 ›› 2021, Vol. 37 ›› Issue (13): 1719-1722.doi: 10.3969/j.issn.1006⁃5725.2021.13.015

• 临床研究 • 上一篇    下一篇

妊娠合并血液病导致血小板减少行剖宫产术采用不同麻醉方式的产妇和胎儿预后:一项单中心12年回顾性研究

窦豆1, 张红1, 冯艺1 张晓红2, 姜陆洋1   

  1. 北京大学人民医院 1 麻醉科,2 产科(北京 100044)

  • 出版日期:2021-07-10 发布日期:2021-07-10
  • 通讯作者: 姜陆洋 E⁃mail:jiangly1018@hotmail.com

Prognosis on different applications of anesthesia for thrombocytopenia induced by hematologic diseases during cesarean section:A 12⁃year single⁃center retrospective study

 DOU Dou,ZHANG Hong,FENG Yi ZHANG XiaoHong,JIANG Luyang.    

  1. Department of Anesthesiology,Peking University People′ s Hospital,Beijing 100044,China 

  • Online:2021-07-10 Published:2021-07-10
  • Contact: JIANG Luyang E⁃mail:jiangly1018@hotmail.com

摘要:

目的 探讨妊娠合并血液病导致血小板减少产妇行剖宫产术不同麻醉方式的应用。方法 回顾过去 12 年血液病导致血小板减少产妇行剖宫产术 297 例,根据不同麻醉方式分为全身麻醉(general anesthesia,GA)组和局部麻醉(local anesthesia,LA)组,获取产妇一般资料、术前日血常规及凝血功能检查 结果、围产期产科及新生儿资料,并电话随访妊娠史和母婴现存身体状况。结果 GA 组术前血小板计数 显著低于 LA 组(P < 0.05)。LA 组具有更高新生儿 5 min Apgar 评分和术后镇痛使用率(P < 0.05)。母婴现 存结局两组间差异无统计学意义(P > 0.05)。结论 血液病导致血小板减少产妇行剖宫产术,一般情况 较差(血小板计数低下、多项血液指标异常、ASA Ⅳ⁃Ⅴ级等)首先考虑全身麻醉,如无禁忌则椎管内麻醉 为最优选择。不同麻醉方式不会对术后母婴结局产生明显影响。

关键词:

血小板减少, 剖宫产术, 麻醉, 预后

Abstract:

Objective To explore the different applications of anesthesia for hematologic diseases⁃induced thrombocytopenia in cesarean section. Methods A total of 297 cases with hematologic diseases⁃induced thrombo⁃ cytopenia who underwent cesarean section in the past 12 years were analyzed retrospectively. Patients were divided into general anesthesia(GA)and local anesthesia(LA)groups. General data of patients,blood routine indexes and coagulation function indexes before surgery and obstetric data were acquired. The pregnancy history and pres⁃ ent outcome of puerperas and children were collected by phone call. Results The account of planet before surgery of group GA were significantly lower than that of group LA(P < 0.05). The Apgar scores at 5 min after delivery and the rate of postoperative analgesia were higher in group LA(P < 0.05). There were no significant differences in the present outcome of puerperal physical conditions and fetal growth(P > 0.05). Conclusions For puerperas with serious hematologic conditions(thrombocytopenia,a series of abnormal blood indexes,ASA physical status Ⅳ or Ⅴ and so on),general anesthesia was recommended. Intravertebral anesthesia could be the best choice if there were no contraindications in patients. There was no significant difference in the prognosis of mothers and children between general anesthesia and local anesthesia.

Key words:

thrombocytopenia, cesarean section, anesthesia, prognosis