实用医学杂志 ›› 2023, Vol. 39 ›› Issue (3): 267-273.doi: 10.3969/j.issn.1006⁃5725.2023.03.001

• 指南 •    下一篇

初级保健和内分泌临床中非酒精性脂肪肝诊断和治疗的临床实践指南要点与解读

牛春燕 陈跃 宋用强    

  1. 南京市溧水区人民医院消化内科(南京 211200)

  • 出版日期:2023-02-10 发布日期:2023-02-10

Key points of the American Association of Clinical Endocrinology Clinical Practice Guideline for the diagno⁃ sis and management of nonalcoholic fatty liver disease in primary care and endocrinology clinical settings co ⁃sponsored

NIU Chunyan,CHEN Yao,SONG Yongqiang.   

  1. Department of Digestive Diseases,Lishui People′ s Hospital,Nanjing 211200,China 

  • Online:2023-02-10 Published:2023-02-10
  • Supported by:
    溧水区人民医院引进人员科研启动专项经费(编 号:2021YJ02),南京市卫生科技发展专项资金项目计划(编 号:YKK22240)

摘要:

由于肥胖和 2 型糖尿病(type 2 diabetes mellitus,T2DM)发病率的增加,非酒精性脂肪性肝病 nonalcoholic fatty liver disease,NAFLD)已达到流行程度,因此需要内分泌科和初级保健临床医生共同参 与其早期诊断和管理。T2DM 和心血管疾病(cardiovascular disease,CVD)是 NAFLD 的最重要肝外伴发病, 因此 NAFLD 的管理涉及生活方式、体质量、血压、血糖、血脂各方面,还应包括肝硬化的预防。本指南系 统阐述了成人和儿童 NAFLD 的预防、诊断、治疗策略,为内分泌学家、初级保健临床医生、卫生保健专业 人员和其他相关专业人员提供了有关NAFLD 诊断和管理的循证建议。

关键词:

肥胖, 2 型糖尿病, 非酒精性脂肪性肝病, 管理, 指南

Abstract:

The increasing incidences of obesity and type 2 diabetes mellitus(T2DM)lead to the preva⁃ lence of nonalcoholic fatty liver disease(NAFLD),which needs its early diagnosis and management by the doctors both in primary care and endocrinology. As T2DM and cardiovascular disease are extrahepatically concomitant,the treatment of NAFLD involves intervention of life style,management of body weight,blood pressure,blood glucose and blood lipid as well as prevention of hepatic cirrhosis. This papers is to interpret the key points of the American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings Co⁃sponsored by the American Association for the Study of Liver Diseases so as to make some evidence ⁃based suggestions on the prevention,diagnosis and treatment strategy for adult and children NAFLD patients.

Key words:

type 2 diabetes mellitus, nonalcoholic fatty liver disease, clinical practice guideline, guidline