实用医学杂志 ›› 2021, Vol. 37 ›› Issue (2): 201-204.doi: 10.3969/j.issn.1006⁃5725.2021.02.014

• 临床研究 • 上一篇    下一篇

术前多模态MRI检查与颅内脑膜瘤患者术后复发及高组织学分级的关系

黄德尤, 廖莎卢德伟李娜罗起胜, 陆海善, 李滢   

  1. 右江民族医学院附属医院1 放射科,2 神经外科,3 病理科(广西百色 533000);4 湖南省常德市第一人民医院影像科(湖南常德 415003)
  • 出版日期:2021-01-25 发布日期:2021-01-25
  • 通讯作者: 李滢 E⁃mail:shizi298878@163.com
  • 基金资助:
    广西壮族自治区卫生和计划生育委员会科技计划项目(编号:Z2016425);百色市科学研究与技术开发计划项目基金(编号:百科计 20140917)

Preoperative multimodal MRI was associated with postoperative recurrence and high histological grade in patients with intracranial meningiomas

HUANG Deyou,LIAO Sha,LU Dewei,LI Na,LUO Qisheng,LU Haishan,LI Ying   

  1. Department of Radiology,Affiliated Hospital of Youjiang Medical College for Nationalities,Baise 533000,China
  • Online:2021-01-25 Published:2021-01-25
  • Contact: LI Ying E⁃mail:shizi298878@163.com

摘要:

目的 评价术前多模态 MRI 检查与颅内脑膜瘤患者术后复发及高组织学分级的关系。 方法 选择 2016 1 月至 2019 6 月我院手术治疗的脑膜瘤患者 100 例,术后根据 WHO 脑膜瘤组织学分 级标准分为低级别组(Ⅰ-Ⅱ级)53 例和高级别组(Ⅲ-Ⅳ)47 例,术后随访观察 1 年,复发患者为 18 例(复 发组),未复发患者为 82 例(未复发组),所有患者术前均行常规及增强磁共振成像(MRI)、磁共振张量成 像(DTI)及磁共振波谱成像(MRS)检查,采用 Logistic 回归分析高级别组和复发组脑膜瘤患者相关影响因 素。结果 复发组与未复发组在肿瘤部位、肿瘤大小、边界、强化灶、ADC 值、FA 值、Cho/NAA、Cho/Cr NAA/Cr 上比较,差异有统计学意义(P < 0.05);高级别组与低级别组在肿瘤大小、边界、强化灶、水肿程度、 ADC 值、FA 值、Cho/NAA、Cho/Cr、NAA/Cr 上比较,差异有统计学意义(P < 0.05);多因素 Logistic 回归分析 示,肿瘤大小、边界、ADC 值、FA 值及 Cho/NAA 值是脑膜瘤复发患者的独立危险因素(P < 0.05);肿瘤大 小、强化灶、ADC 值、FA 值及 Cho/NAA 值是高级别脑膜瘤患者的独立危险因素(P < 0.05)。结论 多模态 MRI 检查有助于判断颅内脑膜瘤患者术后复发及高组织学分级,具有推广应用价值。

关键词:

Abstract: Objective To evaluate the correlation between preoperative multimodal MRI and postoperative recurrence and high histological grade in patients with intracranial meningiomas. Methods One hundred patients with meningioma treated in our hospital from January 2016 to June 2019 were selected,according to the WHO after meningioma histological classification standard is divided into low level group(Ⅰ~Ⅱ)53 cases and high level group(Ⅲ ~ Ⅳ)47 cases,postoperative follow⁃up observation lasted for 1 year. There were 18 patients with recurrence (recurrence group)and 82 patients without recurrence(non⁃recurrence group);All patients underwent conventional and enhanced magnetic resonance imaging(MRI),magnetic resonance tensor imaging(DTI)and magnetic reso⁃ nance spectroscopy(MRS)before surgery;Logistic regression was used to analyze the related influencing factors in patients with high⁃grade and recurrent meningioma. Results Compared with the non⁃recurrent group,there were statistically significant differences in tumor site,tumor size,boundary,enhancement foci,ADC value,FA value Cho/NAA,Cho/Cr,NAA/Cr(< 0.05);The tumor size,boundary,enhancement foci,degree of edema,ADC value FA value,Cho/NAA,Cho/Cr,NAA/Cr were significantly different from those of the low ⁃grade group(< 0.05); Multivariate Logistic regression analysis showed that tumor size,boundary,ADC value,FA value and Cho/NAA value were independent risk factors of meningioma recurrence(< 0.05);Tumor size,enhancement foci,ADC value FA value and Cho/NAA value were independent risk factors of high ⁃ grade meningioma(< 0.05). Conclusion Multimodal MRI is helpful to determine postoperative recurrence and high histological grade in patients with intra⁃cranial meningioma.

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