实用医学杂志 ›› 2022, Vol. 38 ›› Issue (15): 1913-1918.doi: 10.3969/j.issn.1006⁃5725.2022.15.012

• 临床研究 • 上一篇    下一篇

改良髓芯减压植骨联合体外冲击波治疗早期股骨头坏死的疗效 

及松洁1 张隆浩2 徐黎3 杨德金1 吕明1 姜旭1 周一新1    

  1. 1 北京积水潭医院矫形骨科(北京 100035);2 北京积水潭医院冲击波治疗中心(北京 100035); 3 北京积水潭医院影像科(北京 100035)

  • 出版日期:2022-08-10 发布日期:2022-08-10
  • 基金资助:
    国家自然科学基金面上项目(编号:81472139);吴阶平医学基金会临床科研专项资助基金(编号:320.6750.2021⁃20⁃4);北
    京积水潭医院青年人才培养学科新星计划项目(编号:XKXX201814)

Efficacy of advanced core decompression and synthetic bone substitutes grafting combined with an extra⁃ corporeal shock wave for early femoral head necrosis

JI Songjie*,ZHANG Longhao,XU Li,YANG Dejin, LÜ Ming,JIANG Xu,ZHOU Yixin.    

  1. Department of Adult Joint Surgery,Beiing Jishuitan Hospital,Beiing 100035 China 

  • Online:2022-08-10 Published:2022-08-10

摘要:

目的 比较单纯行改良减压植骨手术与减压植骨手术联合冲击波治疗早期股骨头坏死的 近期疗效。方法 收集符合纳入标准的 2018 1 月至 2020 1 月北京积水潭医院矫形骨科及北京朝阳 中西医结合急诊抢救中心骨科收治的早期股骨头缺血坏死患者。按随机原则分为两组,研究组为改 良减压植骨手术联合体外冲击波治疗的病例,对照组为单纯行改良减压植骨手术病例。最终 66 例患者 进入结果分析。其中男 59 髋,女 15 髋。平均年龄(36.8 ± 10.4)岁,左侧 29 例,右侧 37 例。研究组共 30 例(30 髋),术前 VAS 评分为(6.7 ± 0.8),Harris 评分为(68.3 ± 5.0),Kerboul 角(197.7 ± 61.2)°。对照组共 36 例(36 髋),术前 VAS 评分为(6.7 ± 0.9),Harris 评分为(68.3 ± 5.0),Kerboul 角为(201.9 ± 61.4)°。随访时间 分别为 24 个月。记录术后 3、6、12 、24 个月患髋 VAS 评分和 Harris 评分变化。在最后一次随访时进行 MRI 检查,测量 Kerboul 角重新评估坏死区域的大小。结果 两组随访 24 个月,研究组有 4 例塌陷,对照 组有 6 例塌陷。无病例进行全髋关节置换。随访 24 个月研究结束时,两组 VAS 评分和 Harris 评分均比术 前有明显改善。研究组术后 3、6、12 个月的 VAS Harris 评分均优于对照组(P<0.05)。但是随访至 24 月时两组没有差异。研究组 Kerboul 角为(175.0 ± 80.4)°,对照组 Kerboul 角为(193.1 ± 73.6)°,两组均比术 前改善,但两组间差异无统计学意义。研究组△Kerboul 为(-22.7 ± 20.3)°,对照组为(-8.9 ± 26.3)°,研究 组对 kerboul 角的改善更为明显(P = 0.042)。结论 改良髓芯减压人工骨植入手术联合体外冲击波和单 纯改良减压人工骨植入手术治疗早期股骨头坏死的早期疗效令人满意,前者在随访早期比后者可以更好 的减轻疼痛,改善功能,对于Kerboul 角改善也更为明显。

关键词:

股骨头坏死,  , 髓芯减压术,  , 保髋治疗,  , 体外冲击波治疗法,  , 植骨替代

Abstract:

Objective To compare the short ⁃term effect of advanced core decompression(ACD)plus synthetic bone substitutes(SBS)grafting alone with ACD+SBS combined with extracorporeal shock wave therapy (ESWT)for early ⁃stage osteonecrosis of the femoral head(ONFH). Methods Patients who met the inclusion criteria from January 2018 to January 2020 were randomly divided into two groups. The research group was the case of ACD+SBS+ESWT,and the control group was the case of ACD+SBS alone. Finally,66 patients entered the result analysis. There were 30 cases(30 hips)in the research group. The preoperative VAS score was(6.7 ± 0.8),the Harris score was(68.3 ± 5.0),and the Kerboul angle was(197.7 ± 61.2)°. There were 36 cases(36 hips)in the control group. The preoperative VAS score was(6.7 ± 0.9),the Harris score was(68.3 ± 5.0),and the Kerboul angle was(201.9 ± 61.4)°. The follow⁃up time was 24 months. The changes in VAS score and Harris score of the affected hip at 3 months,6 months,12 months,and 24 months after operation were recorded. An MRI was performed at the last follow⁃up,and the Kerboul angle was measured to reassess the size of the necrotic area. Results The two groups were followed up for 24 months. There were 4 cases of collapse in the research group and 6 cases in the control group. No patients underwent a total hip replacement. At the end of the 24⁃month follow⁃up study,Significant improvement of VAS and Harris in both groups was seen before surgery. The VAS and Harris scores of the studygroup were better than those of the control group at three months,six months,and 12 months after operation (P < 0.05). However,there was no difference between the two groups at 24 months of follow⁃up. The Kerboul angle of the research group was(175.0 ± 80.4)°,and that of the control group was(193.1 ± 73.6)°. Both groups were improved compared to preoperative,but there was no difference between the two groups. The Δkerboul angle of the study group was(-22.7 ± 20.3)°,and that of the control group was(-8.9 ± 26.3)°. The improvement of the kerboul angle in the study group was significant(P = 0.042). Conclusion ACD + SBS + ESWT and ACD + SBS alone had satisfactory effects in treating early ⁃ stage ONFH. The former better relieved pain and improve function than the latter in the early follow⁃up period,and the improvement of kerboul angle was also more obvious.

Key words:

femur head necrosis, core decompression, hip?preserving surgery, ESWT, bone graft substitutes