关键词:

text-indent:0pt, "> 肛周脓肿, 五黄生肌汤, 倾向评分匹配法

Abstract:

Objective To observe the clinical efficacy of isobaric drainage combined with self ⁃ made WuhuangShengji Decoction wound cavity irrigation in the treatment of multi⁃space perianal abscess，and to explore the application of traditional Chinese medicine. Methods 188 patients with perianal abscess，including 149 in the control group and 39 in the observation group. Propensity score matching method was used to match the baseline of the two groups of patients. There were 33 patients enrolled in each of the two groups with balanced baseline data. The control group used normal saline to wash the wound after the dressing change，while the observation group used WuhuangShengji Decoction to wash the wound. The wound exudation，granulation growth，wound depth，wound healing time，and sloughing time of the wound in the two groups，as well as the hospitalization days，were used to evaluate the efficacy of the two groups of patients. Results After matching，there was no statistical difference in baseline data between the two groups（All P > 0.05）. At 7 days after operation，the score of the observation group was lower than that of the control group，the difference was statistically significant（P < 0.05）；at 5 days and 14 days，the difference was not statistically significant（all P > 0.05）. In the comparison of granulation growth scores， 5 days after surgery，7 days after surgery，14 days after surgery and surgeryafter 21 days，the difference between the observation group and the control group was statistically significant（all P < 0.05）. In comparison of wound depth，14 days（and 21 days）after operation，the difference between the observation group and the control group was statistically significant（all P < 0.05）. However，there was no statistically significant difference in the index 7 days after operation（P > 0.05）. The average wound healing time of the observation group was（33.27±3.43）d， and the control group was（36.94±4.95）d，the difference was statistically significant. There was no significant difference in the time of carrion shedding between the observation group and the control group（P > 0.05）；the average hospital stay of the observation group was（9.97 ± 2.49）d，and the control group was（12.88 ± 3.58）d，the difference was statistically significant（P < 0.05）. Conclusion Following a perianal abscess，using WuhuangSh⁃ engji Decoction to flush the wound cavity can promote wound growth，accelerate wound healing，and shorten the av⁃ erage hospital stay. The effect is superior to standard saline irrigation of the wound cavity.

Key words:

perianal abscess, traditional chinese medicine, propensity score matching