呼气时间常数在学龄期儿童常规通气肺功能中的应用价值

doi:10.3969/j.issn.1006⁃5725.2021.11.011

实用医学杂志 ›› 2021, Vol. 37 ›› Issue (11): 1428-1432.doi: 10.3969/j.issn.1006⁃5725.2021.11.011

呼气时间常数在学龄期儿童常规通气肺功能中的应用价值

张艳丽，王潇，苏爱芳，代富力，王秀芳，张艳，郑月红，蔡春玲，师红可

1 郑州大学第三附属医院儿内科（郑州 450052）；2 漯河市第二人民医院儿内科（河南漯河 462000）； 3 洛阳市妇幼保健院儿内科（河南洛阳 471000）

出版日期:2021-06-10 发布日期:2021-06-10
基金资助:
2019 年度河南省医学科技攻关计划（联合共建）项目（编号：LHGJ20190342）

R725.6 The value of expiratory time constant in routine ventilatory pulmonary function test in school ⁃ aged chil⁃ dren

ZHANG Yanli，WANG Xiao，SU Aifang，DAI Fuli，WANG Xiufang，ZHANG Yan，ZHENG Yuehong，CAI Chunling，SHI Hongke.

Department of Pediatrics，Third Affiliated Hospital of Zhengzhou University，Zhengzhou 450052，China

Online:2021-06-10 Published:2021-06-10

摘要/Abstract

摘要：

目的本文旨在研究呼气时间常数（RCEXP）在学龄期儿童常规通气肺功能测定中的应用价值。方法选择 2018 年 8 月至 2020 年 8 月在郑州大学第三附属医院、河南省漯河市第二人民医院和河南省洛阳市妇幼保健院行常规通气肺功能测定的 442 例学龄期儿童。分析不同性别、年龄和身高儿童 RCEXP的差异性；肺功能正常组分别与不同气道阻塞组之间计算各组的 RCEXP值，并做出相应的 ROC 曲线；探究 RCEXP与肺功能参数之间的关联。结果女童 RCEXP显著小于男童（P＜0.001）、低年龄组 RCEXP显著小于高年龄组（P＜0.05），低身高组 RCEXP显著小于高身高组（P＜0.05）；正常组 RCEXP显著小于气道阻塞组（P＜0.001），RCEXP的 cutoff 值为 0.436；正常组 RCEXP显著小于大气道阻塞组（P＜0.001），RCEXP的 cutoff 值为 0.575；正常组RCEXP显著小于小气道阻塞组（P＜0.001），RCEXP的cutoff 值为0.434。RCEXP与FEV1/FVC%呈负相关。结论学龄期儿童 RCEXP延长提示气道阻塞；RCEXP大于 0.436、0.575、0.434 s 分别提示存在气道阻塞、大气道阻塞和小气道阻塞。

关键词: RCEXP, , 学龄期儿童, , 肺功能, , 气道阻塞, , 应用价值

Abstract:

Objective To investigate the value of Expiratory time constant（RCEXP）in the measurement of routine ventilatory pulmonary function test of school⁃aged children. Methods A total of 442 school⁃aged children received routine pulmonary function measurements in the Third Affiliated Hospital of Zhengzhou University，Luohe Second People′s Hospital and Luoyang Maternal and Children Health Hospital between August 2018 and August 2020 were selected. RCEXP differences between sexes，ages，and heights were investigated，and RCEXP values were calculated between groups with normal lung function and groups with various airway obstructions. Furthermore，the corresponding ROC curves were created. The relationships between RCEXP and pulmonary function parameters were investigated. Results RCEXP of girls was significantly lower than that of boys（P < 0.001），RCEXP of younger age group was significantly lower than that of older age group（P < 0.05），and RCEXP of lower height group was signifi⁃ cantly lower than that of higher height group（P < 0.05）；The RCEXP of girls was significantly lower than that of boys. The RCEXP of low age group was significantly lower than that of high age group and the RCEXP of low height group was significantly lower than that of high height group（P < 0.05）；RCEXP in the normal group was significant⁃ ly lower than that in the airway obstruction group（P < 0.001），and the cutoff value of RCEXP was 0.436. RCEXP in the normal group was significantly lower than that in the large airway obstruction group（P < 0.001），and the cutoff value of RCEXP was 0.575. In addition，RCEXP in the normal group was significantly lower than that in the small airway obstruction group（P < 0.001），and the cutoff value of RCEXP was 0.434；RCEXP was negatively correlated with FEV1/FVC%. Conclusion High RCEXP in school⁃aged children suggests airway obstruction. Airway obstruc⁃ tion，large airway obstruction，and minor airway obstruction were indicated by RCEXP values greater than 0.436 s，0.575 s，and 0.434 s，respectively.

Key words:

RCEXP, school ? aged children, pulmonary function, airway obstruction, application value

张艳丽王潇苏爱芳代富力王秀芳张艳郑月红蔡春玲师红可 .

呼气时间常数在学龄期儿童常规通气肺功能中的应用价值 [J]. 实用医学杂志, 2021, 37(11): 1428-1432.

ZHANG Yanli, WANG Xiao, SU Aifang, DAI Fuli, WANG Xiufang, ZHANG Yan, ZHENG Yuehong, CAI Chunling, SHI Hongke. .

R725.6 The value of expiratory time constant in routine ventilatory pulmonary function test in school ⁃ aged chil⁃ dren [J]. The Journal of Practical Medicine, 2021, 37(11): 1428-1432.

[1]	周结学刘东蒙善东申升朱春丽王晓庄锦炀马娟. 体外光化学疗法对大鼠肾移植抗排斥反应的研究[J]. 实用医学杂志, 2023, 39(8): 944-947.
[2]	祁慧黄亚雄周国强曹静 . 不同抗逆转录病毒治疗方案对HIV/AIDS患者CK⁃MB、CK的影响 [J]. 实用医学杂志, 2023, 39(8): 958-962.
[3]	陈璐刘源. 山姜素靶向调控Nrf2抑制H9C2细胞氧化应激反应 [J]. 实用医学杂志, 2023, 39(7): 813-818.
[4]	潘毅陈军喜闫智杰夏芝辉 . 白术内酯Ⅲ调节AMPK/SIRT1/NF⁃κB信号通路对脓毒症大鼠肝损伤的影响 [J]. 实用医学杂志, 2023, 39(7): 827-832.
[5]	谢永铮孙新房孙俊聪王朝阳郑立史朝晖 . 不同手术方式对肝硬化食管胃底静脉曲张破裂出血的疗效 [J]. 实用医学杂志, 2023, 39(7): 860-865.
[6]	王贤方刘志东张园黄常镜张海飞余丽琼钟炜 . 南方汉族人群ABCG2 rs2231142和SLC2A9 rs3733591 单核苷酸多态性与高尿酸血症及心血管危险因素的相关性 [J]. 实用医学杂志, 2023, 39(7): 875-880.
[7]	严健亮, 景蓉蓉谢泽宇崔明. 机器学习在胃癌生物标志物挖掘中的应用进展 [J]. 实用医学杂志, 2023, 39(6): 783-787.
[8]	李明娟李学欣刘力 . 短时间机械通气对脓毒症大鼠膈肌功能的影响 [J]. 实用医学杂志, 2023, 39(5): 579-590.
[9]	张芮王志涛刘德君马恒 . 不同剂量右美托咪定对瑞马唑仑致患者意识消失ED95及应激反应的影响 [J]. 实用医学杂志, 2023, 39(4): 476-480.
[10]	徐瑶, 肖超群周燕莉李娟华刘芳王志坚 . 妊娠期妇女抑郁状态现状与影响因素分析 [J]. 实用医学杂志, 2023, 39(4): 493-498.
[11]	黄婷婷吴海科练梦结杨轩 . 不同频率重复经颅磁刺激联合补阳还五汤对气虚血瘀型卒中患者运动功能的疗效观察 [J]. 实用医学杂志, 2023, 39(4): 499-504.
[12]	王璐洁罗纯黄淑玲林连升张园 . 新冠病毒感染者前白蛋白对淋巴细胞的影响：焦虑和超敏C反应蛋白的中介作用 [J]. 实用医学杂志, 2023, 39(3): 273-277.
[13]	袁峰张书力李少军李敏胡焓童胜雄田佳玉冯丹 . 血清miR⁃21、缺氧诱导因子⁃1α水平在带状疱疹患者治疗前后变化及评估后遗神经痛的分析 [J]. 实用医学杂志, 2023, 39(3): 364-368.
[14]	崔家康高青杰马俊福孟庆良 . circ_0005276靶向miR⁃557调控类风湿关节炎滑膜成纤维细胞的增殖、迁移和侵袭 [J]. 实用医学杂志, 2023, 39(2): 186-191.
[15]	廖志伟朱建曼周同冲郑荣辉. 长链非编码RNA TUG1对鼻咽癌细胞生物学行为及放射敏感性的影响[J]. 实用医学杂志, 2023, 39(2): 209-216.

呼气时间常数在学龄期儿童常规通气肺功能中的应用价值

R725.6 The value of expiratory time constant in routine ventilatory pulmonary function test in school ⁃ aged chil⁃ dren

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价