关键词:

缺血性脑卒中, 口腔卫生, 卒中相关性肺炎, 危险因素, 龋齿, 高龄, 神经功 能缺损, 日常生活活动能力

Abstract:

Objective To analyze the influencing factors and correlation of oral hygiene and stroke⁃associ⁃ ated pneumonia（SAP）in patients with acute ischemic stroke. Methods We performed a cross⁃sectional study by recruiting 331 patients with acute ischemic strokefrom two medical centers. A series of assessments were performed to evaluate the neurological status and habits of oral hygiene. Univariate analyses were performed firstly on the conditions of oral hygiene and occurrence of SAP. Multiple logistic regression analyses were conducted to find risk factors of oral cleanness and SAP in the stroke patients. Results After adjusting the confounders，multivariable logistic regression analysis showed that SAP（OR = 2.219，P = 0.026），dental caries（OR = 1.292，P = 0.005）and age（OR = 1.030，P = 0.006）were the risk factors for oral cleanness in those stroke patients，while the score of Barthel index（OR = 0.986，P = 0.019）was a protective factor. BOAS score（OR = 1.972，P < 0.001）and NIHSS score（OR = 1.322，P < 0.001）were the risk factors for SAP. Conclusion The abnormality of oral cleanness and SAP are the and mutually acting risk factors in patients with acute ischemic stroke. Protecting oral hygiene may be helpful for SAP prevention.

Key words:

ischemicstroke, oral hygiene, stroke?associated pneumonia, neurological deficit, risk factors, dental caries, aging, activities of daily living