实用医学杂志 ›› 2021, Vol. 37 ›› Issue (14): 1815-1819.doi: 10.3969/j.issn.1006⁃5725.2021.14.008

• 临床研究 • 上一篇    下一篇

富血小板血浆治疗狭窄性腱鞘炎的临床研究

孙劲1 ,王文雪2, 李霄3   

  1. 三峡大学第三临床医学院国药葛洲坝中心医院1 骨科,3 检验科(湖北宜昌 443002);2 三峡大学医学院 (湖北宜昌 443002)

  • 出版日期:2021-07-25 发布日期:2021-07-25
  • 通讯作者: 李霄 E⁃mail:376940351@qq.om
  • 基金资助:

    湖北省卫生计生委联合基金立项面上项目(编号:WJ2019H568);宜昌市医疗卫生科研项目(编号:A19⁃301⁃49)

Clinical study of platelet rich plasma in the treatment of flexor tendon stenosing tenosynovitis 

SUN Jin* WANG Wenxue,LI Xiao.   

  1. Department of Orthopedics,the Third Clinical Medical College of China Three Gorges Uni⁃ versity,Gezhouba Central Hospital of Sinopharm,Yichang 443002,China

  • Online:2021-07-25 Published:2021-07-25
  • Contact: LI Xiao E⁃mail:376940351@qq.om

摘要:

目的 探讨富血小板血浆(platelet rich plasma,PRP)治疗屈指肌腱狭窄性腱鞘炎的临床疗 效。方法 选取 2017 1 月至 2019 12 月我院诊治的 65 例屈指肌腱狭窄性腱鞘炎患者,采用随机数字 表法随机分成观察组 32 例,对照组 33 例。观察组行 PRP 注射治疗,对照组行曲安奈德注射治疗。分析两 组患者治疗前与治疗后第 2、4、8 周手指关节活动度及视觉模拟疼痛评分(VAS)、治疗前后 Quinnell 评分、 治疗总有效率、并发症发生情况。结果 两组治疗前与治疗后第 2 周视觉模拟疼痛评分(VAS)及手指关 节活动度、治疗前 Quinnell 评分、治疗后并发症发生率比较,差异无统计学意义(P>0.05);两组治疗后第 4 周与第 8 周视觉模拟疼痛评分(VAS)及手指关节活动度、治疗后 Quinnell 评分、治疗总有效率比较,差异有 统计学意义(P<0.05)。结论 富血小板血浆(PRP)治疗屈指肌腱狭窄性腱鞘炎疗效显著,可有效缓解临 床症状,缩短疾病病程,无并发症风险,是一种值得推广的治疗方式

关键词:

富含血小板血浆, 屈指肌腱, 狭窄性腱鞘炎, 曲安奈德 ,

Abstract:

Objective To explore the clinical effect of platelet rich plasma(Platelet rich plasma PRP)for the treatment of flexor tendon stenosing tenosynovitis. Methods From January 2017 to December 2019,65 patients with flexor tendon stenosing tenosynovitis were diagnosed and treated at our hospital using the random number table method,and were randomly divided into 32 cases in observation group and 33 cases in control group. The observa⁃ tion group received PRP injections,while the control group received triamcinolone acetonide injections. Before and after treatment,finger range of motion and visual analogue pain score(VAS),Quinnell score,total effective rate of treatment,and complications were assessed. Results There was no statistically significant difference in VAS Quinnell,or complications between the two groups before and after treatment(P > 0.05). At 4 and 8 weeks after treatment,the VAS,range of motion of finger joints,Quinnell score after treatment,and total effective rate were compared between the two groups,and the differences were statistically significant (P < 0.05). Conclusion Platelet rich plasma(PRP is an effective treatment for flexor tendon stenosing tenosynovitis,which can effectively alleviate the clinical symptoms,shorten the course of disease,and has no risk of complications. It is a treatment that should be promoted.

Key words:

platelet rich plasma, flexortendon, stenosing tenosynovitis, triamcinolone acetonide